23 documents found, page 1 of 3
Potential of Marine Biomolecules: Advances in Extraction and Applications of Pr...
Sousa, Gabriela; Ferreira-Dias, Suzana; Tecelão, Carla; Alves, Vítor D.Oceans are increasingly viewed as a new frontier for economic development, contributing to the bridge between food industry, sea bioeconomy, and health. Nowadays, oceans are under attention as a strategy for creating opportunities and driving innovation, and their vital importance will become even more evident in the years to come. Therefore, it is crucial to study oceans under a holistic approach, taking the m...
Burden of Disease and Cost of Illness of Triple-Negative Breast Cancer in Portu...
Silva, Joana; Sousa, Gabriela; Costa, Luís; Brito, Margarida; Oliveira, Sónia; Rodrigues, Bernardo; Ferreira, João; Borges, Margarida; Miguel, LuísBackground: Triple-negative breast cancer accounts for 15% of all breast cancer cases, and it has a lower survival rate and higher incidence of early recurrence, particularly during the first 10 years after diagnosis. Objective: This study aimed to estimate the cost and burden of triple-negative breast cancer among the female population in 2019 in Portugal from a societal perspective. Methods: The prevalence of...
Adjuvant Hyperthermic Intravesical Chemotherapy in Intermediate- and High-Risk ...
Magalhães, Joana C; Sousa, Maria João; Basto, Raquel; Fraga, Teresa; Gomes, Inês; Fernandes, Catarina; Mariano, Mónica; Paulo, Judy; Madeira, PedroIntroduction: Non-muscle invasive bladder cancer (NMIBC) is a frequently diagnosed neoplasm, which is typically managed with transurethral resection of bladder tumor (TURBT) eventually followed by intravesical therapies. Bacillus Calmette-Guérin (BCG) is used as first-line adjuvant treatment in high- (HR) and intermediate-risk (IR) NMIBC, although, in the latter, mitomycin C (MMC) may also be used. Multiple lim...
Relapsed Ovarian Cancer patients with ascites and/or pleural effusion still ben...
Rebordão-Pires, Mariana; Estrada, Marta F.; Gomes, António; Silva, Filipa; Baptista, Carlota; Ramos, Maria João; Fortuna, Ana; Simões, Pedro) Background: Relapsed HGSOC with ascites and/or pleural effusion is a poor-prognostic population and poorly represented in clinical studies. We questioned if these patients are worth treating. In other words, if these patients received the most effective treatment, would it change the course of this disease? To our knowledge this is the first real-life study to evaluate this question in this low-survival popul...
Tratamento do Cancro da Mama HER2-Positivo: Posicionamento de um Painel de Peritos
Afonso, Noémia; Cortes, Paulo; Cardoso, Fátima; Costa, Luís; Coutinho, Camila; Moreira, António; Passos Coelho, José Luís; Pereira, DeolindaThe overexpression of the human epidermal growth factor receptor type 2 (HER2) is present in 20% of all breast cancers and has known prognostic value, associated with a higher risk of recurrence and mortality. Management of these patients has evolved significantly in recent years due to advances in the identification of biomarkers and in treatment efficacy. This article reviews key aspects of the neoadjuvant an...
Enrichment of sunflower oil with ultrasound-assisted extracted bioactive compou...
Sousa, Gabriela; Alves, Mariana I.; Neves, Marta; Tecelão, Carla; Ferreira-Dias, SuzanaCrithmum maritimum L., or sea fennel, is an edible halophyte plant, rich in phenolic compounds with antioxidant and antimicrobial activities, that naturally grows in Mediterranean coasts. This study aims to incorporate bioactive compounds extracted from lyophilized Crithmum maritimum to sunflower oil assisted by ultrasounds (UAE), to improve its biological value and oxidative stability. UAE conditions were opti...
Enrichment of Sunflower Oil with Ultrasound-Assisted Extracted Bioactive Compou...
Sousa, Gabriela; Alves, Mariana I.; Neves, Marta; Tecelão, Carla; Ferreira-Dias, SuzanaCrithmum maritimum L., or sea fennel, is an edible halophyte plant, rich in phenolic compounds with antioxidant and antimicrobial activities, that naturally grows in Mediterranean coasts. This study aims to incorporate bioactive compounds extracted from lyophilized Crithmum maritimum to sunflower oil assisted by ultrasounds (UAE), to improve its biological value and oxidative stability. UAE conditions were opti...
Patient Blood Management – is its application possible in oncology?
Santos, Alexandra; Oliveira, Ana; Raimundo, Ana; Coelho, Andreia; Monteiro, Andreia; Araújo, António; Moreira, António; Nunes, António; Fonseca, CândidaPatient blood management (PBM) is a safe approach aiming to improve a patient’s medical and surgical management in ways that boost and conserve their own blood. Approximately 32% to 60% of oncology patients have iron deficiency – the majority of whom are anaemic – therefore, it is important to discuss strategies to avoid excessive blood usage and the reduction of tumour progression and cancer recurrence. In thi...
Cancer Network for Welfare Aging (NEWAYS): Strategies for Optimizing the Care o...
Pimentel, Francisco Luís; Veríssimo, Manuel; Oliveira, Carlos; Soares, Jorge; Sousa, Gabriela; Martinho da Silva, Paula; Vilaverde Cabral, ManuelThe project NEWAYS − Cancer Network for Welfare Aging aimed to raise national awareness for Geriatric Oncology issue in Portugal. To do so, it set to define strategic courses of action in four preponderant areas in the care of elderly with cancer, in order to foster its optimization and promote the development of Geriatric Oncology policies in Portugal: clinic, economics and health policy, epidemiologic and soc...
Optimization of ultrasound-assisted extraction of bioactive compounds from Pelv...
Sousa, Gabriela; Trifunovska, Marija; Antunes, Madalena; Miranda, Isabel; Moldão-Martins, Margarida; Alves, Vitor D.; Vidrih, Rajko; Lopes, Paula AllenIn this study, Pelvetia canaliculata L. macroalga, collected from the Atlantic Portuguese coast, was used as a source of bioactive compounds, mostly antioxidants, to incorporate them in sunflower oil with the aim of increasing its biological value and oxidative stability. The lyophilized alga was added to the oil, and ultrasound‐assisted extraction (UAE) was performed. Algae concentration and UAE time varied fo...