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Data publication with the structural biology data grid supports live analysis

Meyer, P; Socias, S; Key, J; Ransey, E; Tjon, E; Buschiazzo, A; Lei, M; Botka, C; Withrow, J; Neau, D; Rajashankar, K; Anderson, K; Baxter, R

Access to experimental X-ray diffraction image data is fundamental for validation and reproduction of macromolecular models and indispensable for development of structural biology processing methods. Here, we established a diffraction data publication and dissemination system, Structural Biology Data Grid (SBDG; data. sbgrid. org), to preserve primary experimental data sets that support scientific publications....


The unique regulation of iron-sulfur cluster biogenesis in a Gram-positive bact...

Santos, JA; Alonso-García, N; Macedo-Ribeiro, S; Pereira, PJ

Iron-sulfur clusters function as cofactors of a wide range of proteins, with diverse molecular roles in both prokaryotic and eukaryotic cells. Dedicated machineries assemble the clusters and deliver them to the final acceptor molecules in a tightly regulated process. In the prototypical Gram-negative bacterium Escherichia coli, the two existing iron-sulfur cluster assembly systems, iron-sulfur cluster (ISC) and...


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