3 documents found, page 1 of 1
The Updated Role of Ultrasound in Assessing Dermatological Manifestations in Sy...
Ruaro, Barbara; Santiago, Tânia; Hughes, Michael; Lepri, Gemma; Poillucci, Gabriele; Baratella, Elisa; Salton, Francesco; Confalonieri, MarcoSystemic sclerosis (SSc), an autoimmune connective tissue disease, characterized by skin fibrosis, increased dermal thickness and microvascular involvement. Fibroblasts and myofibroblasts deposit excessive amounts of collagenous and non-collagenous extracellular matrix components in the skin. This leads to microvascular abnormalities and Raynaud's phenomenon, with painful digital ulcers (DU) at the fingertips a...
Mixed connective tissue disease : state of the art on clinical practice guidelines
Chaigne, Benjamin; Scirè, Carlo Alberto; Talarico, Rosaria; Alexander, Tobias; Amoura, Zahir; Avcin, Tadej; Beretta, Lorenzo; Doria, AndreaMixed connective tissue disease (MCTD) is a complex overlap disease with features of different autoimmune connective tissue diseases (CTDs) namely systemic sclerosis, poly/dermatomyositis and systemic lupus erythematous in patients with antibodies targeting the U1 small nuclear ribonucleoprotein particle. In this narrative review, we summarise the results of a systematic literature research which was performed ...
Undifferentiated connective tissue disease : state of the art on clinical pract...
Antunes, Margarida; Scirè, Carlo Alberto; Talarico, Rosaria; Alexander, Tobias; Avcin, Tadej; Belocchi, Chiara; Doria, Andrea; Franceschini, FrancoThe term 'undifferentiated connective tissue disease' (UCTD) is generally used to describe clinical entities characterised by clinical and serological manifestations of systemic autoimmune diseases but not fulfilling the criteria for defined connective tissue diseases (CTDs). In this narrative review, we summarise the results of a systematic literature research, which was performed as part of the ERN ReCONNET p...