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Systematic analysis of RhoGEF/GAP localizations uncovers regulators of mechanos...
Pietro, F; Osswald, M; Heras, JM; Cristo, I; López-Gay, J; Wang, Z; Pelletier, S; Gaugué, I; Leroy, A; Martin, C; Morais-de-Sá, E; Bellaïche YCell proliferation is central to epithelial tissue development, repair, and homeostasis. During cell division, small RhoGTPases control both actomyosin dynamics and cell-cell junction remodeling to faithfully segregate the genome while maintaining tissue polarity and integrity. To decipher the mechanisms of RhoGTPase spatiotemporal regulation during epithelial cell division, we generated a transgenic fluorescen...
Date: 2023
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Origin: Repositório Aberto da Universidade do Porto