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Prevalence of anogenital infection by Human Papillomavirus (HPV) in users of im...

Roncada, Eduardo Vinícius Mendes; Carapeba, Murilo de Oliveira Lima; Levi, José Eduardo; Abreu, Marilda Aparecida Milanez Morgado de

Objective: To compare the prevalence of anogenital infection by human papillomavirus (HPV) in immunobiological users being treated for immune-mediated chronic inflammatory diseases with that in non-users. Methodology: The total sample studied consisted of 228 participants divided into 2 groups: 114 users and 114 non-users of immunobiological, cytotoxic or corticosteroid therapy, with non-psoriasis dermatoses an...

Data: 2022   |   Origem: Oasisbr

Zika virus infection among symptomatic patients from two healthcare centers in ...

Tozetto-Mendoza, Tania Regina; Avelino-Silva, Vivian Iida; Fonseca, Silvia; Claro, Ingra Morales; Paula, Anderson Vicente de; Levin, Anna Sara

Zika virus (ZIKV) clinical presentation and frequency/duration of shedding need further clarification. Symptomatic ZIKV-infected individuals identified in two hospitals in Sao Paulo State, Brazil, were investigated regarding clinical characteristics, shedding in body fluids, and serodynamics. Ninety-four of 235 symptomatic patients (Site A: 58%; Site B: 16%) had Real-Time PCR-confirmed ZIKV infection; fever, he...

Data: 2019   |   Origem: Oasisbr

HPV in women assisted by the family health strategy

Ayres, Andréia Rodrigues Gonçalves; Silva, Gulnar Azevedo e; Teixeira, Maria Teresa Bustamante; Duque, Kristiane de Castro Dias

-; OBJECTIVE: Estimate the prevalence of cervical HPV infection among women assisted by the Family Health Strategy and identify the factors related to the infection. METHODS: A cross-sectional study involving 2,076 women aged 20–59 years old residing in Juiz de Fora, State of Minas Gerais, who were asked to participate in an organized screening carried out in units were the Family Health Strategy had been imple...

Data: 2018   |   Origem: Oasisbr

Loss of Raf kinase inhibitor protein expression is associated with human papill...

Bidinotto, Lucas Tadeu; Véo, Carlos A. R.; Loaiza, Edgar Aleman; Ribeiro, Guilherme G.; Lorenzi, Adriana T.; Rosa, Luciana Albina Reis

There has been an increase in the incidence of anal cancer in the past two decades, with squamous cell carcinoma (SCC) being the most frequent histological type identified. Among the risk factors, high-risk human papillomavirus (HPV) infection is the most pervasive. Raf kinase inhibitor protein (RKIP) is expressed in a number of normal human tissues and previous studies have demonstrated the prognostic value of...


Influence of prior knowledge of human papillomavirus status on the performance ...

Martins, Toni Ricardo; Longatto, Adhemar; Cohen, Diane; Viscondi, Juliana Yukari Kodaira; Fuza, Luiz Mario; Cury, Lise; Villa, Luisa Lina

This study aimed to evaluate the influence of prior knowledge of human papillomavirus (HPV) status in cervical cytopathology readings.


Characterization of topoisomerase II α and minichromosome maintenance protein 2...

Scapulatempo-Neto, Cristovam; Veo, Carlos; Fregnani, José Humberto T.G.; Lorenzi, Adriana; Mafra, Allini; Melani, Armando G.F.

The present study aimed to ascertain the significance of topoisomerase II alpha (TOP2A) and minichromosome maintenance protein (MCM) 2 expression in anal carcinoma. A total of 75 anal lesions were retrieved from the files of the Department of Pathology of Barretos Cancer Hospital (Barretos, Brazil) in order to verify the human papillomavirus (HPV) statuses of these lesions and characterize the immunohistochemic...


Validation of QF-PCR for prenatal diagnoses in a Brazilian population

de Moraes, Renata Wendel; de Carvalho, Mario Henrique Burlacchini; de Amorim-Filho, Antonio Gomes; Francisco, Rossana Pulcineli Vieira

OBJECTIVES: Quantitative fluorescence polymerase chain reaction (QF-PCR) is a rapid and reliable method for screening aneuploidies, but in Brazil, it is not used in public services. We investigated the accuracy of QF-PCR for the prenatal recognition of common aneuploidies and compared these results with cytogenetic results in our laboratory. METHOD: A ChromoQuant QF-PCR kit containing 24 primer pairs targeting ...

Data: 2017   |   Origem: Oasisbr

A low-cost HPV immunochromatographic assay to detect high-grade cervical intrae...

Mariano, Vânia Sammartino; Lorenzi, Adriana Tarlá; Scapulatempo-Neto, Cristovam; Stein, Maíra Degiovani; Resende, Julio Cesar Possati

Objective To evaluate the reproducibility and accuracy of the HPV16/18-E6 test. Methods The study population was comprised of 448 women with a previously abnormal Pap who were referred to the Barretos Cancer Hospital (Brazil) for diagnosis and treatment. Two cervical samples were collected immediately before colposcopy, one for the hr-HPV-DNA test and cytology and the other for the HPV16/18-E6 test using high-a...


Low mutation percentage of KRAS and BRAF genes in Brazilian anal tumors

Bidinotto, Lucas Tadeu; Veo, Carlos A. R.; Loaiza, Edgar Antonio Alemán; França, Alessandra Paulino Santos de; Lorenzi, Adriana Tarla

Anal cancer is a rare type of digestive tract disease, which has had a crescent incidence in a number of regions. Carcinomas are most frequently found, with squamous cell carcinoma (SCC) comprising similar to 95% of all anal tumors. The major risk factor for development of this type of tumor is human papillomavirus (HPV) infection. However, previous studies have identified patients with anal cancer that are HPV...



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