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Erlangen Score as a tool to predict progression from mild cognitive impairment ...

Baldeiras, Inês; Santana, Isabel; Leitão, Maria João; Vieira, Daniela; Duro, Diana; Mroczko, Barbara; Kornhuber, Johannes; Lewczuk, Piotr

Background: The previously described and validated Erlangen Score (ES) algorithm enables interpretation of the cerebrospinal fluid (CSF) biomarkers of Alzheimer’s disease (AD), ordering them on an ordinal scale: from neurochemically normal (ES = 0) through improbable AD (ES = 1), possible AD (ES = 2 or 3), to probable AD (ES = 4). Here we assess the accuracy of the ES in predicting hazards of progression from t...


The Central Biobank and Virtual Biobank of BIOMARKAPD: A Resource for Studies o...

Reijs, Babette L R; Teunissen, Charlotte E; Goncharenko, Nikolai; Betsou, Fay; Blennow, Kaj; Baldeiras, Inês; Brosseron, Frederic; Cavedo, Enrica

Biobanks are important resources for biomarker discovery and assay development. Biomarkers for Alzheimer's and Parkinson's disease (BIOMARKAPD) is a European multicenter study, funded by the EU Joint Programme-Neurodegenerative Disease Research, which aims to improve the clinical use of body fluid markers for the diagnosis and prognosis of Alzheimer's disease (AD) and Parkinson's disease (PD). The objective was...


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