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Early immune response against Fonsecaea pedrosoi requires Dectin-2-mediated Th1...

Siqueira, Isaque Medeiros; Wüthrich, Marcel; Li, Mengyi; Wang, Huafeng; Las-Casas, Lucas de Oliveira; Castro, Raffael Júnio Araújo de; Klein, Bruce

Chromoblastomycosis (CBM) is a chronic worldwide subcutaneous mycosis, caused by several dimorphic, pigmented dematiaceous fungi. It is difficult to treat patients with the disease, mainly because of its recalcitrant nature. The correct activation of host immune response is critical to avoid fungal persistence in the tissue and disease chronification. CD4+ T cells are crucial for the development of protective i...

Date: 2022   |   Origin: Oasisbr
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