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miR-139-5p protects septic mice with acute lung injury by inhibiting Toll-like ...

Zhang, Xiuxiu; Liu, Xin; Chang, Rui; Li, Yue

OBJECTIVES: To investigate the role of miR-139-5p and the TLR4/MyD88/NF-kB signaling pathway in acute lung injury in septic mice. METHOD: A total of 140 healthy male SPF C57BL/6 mice were divided into seven groups, i.e., Normal, Control, NC, miR-139-5p mimic, miR-139-5p inhibitor, TAK-242, and miR-139-5p inhibitor+TAK-242 groups. The levels of miR-139-5p, proteins related to the TLR4/MyD88/NF-kB signaling pathw...

Date: 2021   |   Origin: Oasisbr

Global chronic total occlusion crossing algorithm: JACC state-of-the-Art review

Wu, Eugene B.; Brilakis, Emmanouil S.; Mashayekhi, Kambis; Tsuchikane, Etsuo; Alaswad, Khaldoon; Araya, Mario; Avran, Alexandre; Azzalini, Lorenzo

The authors developed a global chronic total occlusion crossing algorithm following 10 steps: 1) dual angiography; 2) careful angiographic review focusing on proximal cap morphology, occlusion segment, distal vessel quality, and collateral circulation; 3) approaching proximal cap ambiguity using intravascular ultrasound, retrograde, and move-the-cap techniques; 4) approaching poor distal vessel quality using th...


Global chronic total occlusion crossing algorithm

Wu, Eugene B.; Brilakis, Emmanouil S.; Mashayekhi, Kambis; Tsuchikane, Etsuo; Alaswad, Khaldoon; Araya, Mario; Avran, Alexandre; Azzalini, Lorenzo

The authors developed a global chronic total occlusion crossing algorithm following 10 steps: 1) dual angiography; 2) careful angiographic review focusing on proximal cap morphology, occlusion segment, distal vessel quality, and collateral circulation; 3) approaching proximal cap ambiguity using intravascular ultrasound, retrograde, and move-the-cap techniques; 4) approaching poor distal vessel quality using th...


Bifunctional porous cobalt phosphide foam for high-current-density alkaline wat...

Li, Yue; Wei, Bin; Yu, zhipeng; Bondarchuk, Oleksandr; Araujo, Ana; Amorim, Isilda; Zhang, Nan; Xu, Junyuan; Neves, Isabel C.; Liu, Lifeng

Alkaline water electrolysis is a cost-effective approach to hydrogen production, but it suffers from low operational current densities (typically ⤠500 mA cm-2) and thereby a low hydrogen production rate. Herein, we report the fabrication of self-supported porous cobalt phosphide (Co-P) foam by electrochemical anodization of commercially available cobalt foam, followed by thermal oxidation and subsequent phosp...


Guiding principles for chronic total occlusion percutaneous coronary interventi...

Brilakis, Emmanouil S.; Mashayekhi, Kambis; Tsuchikane, Etsuo; Abi Rafeh, Nidal; Alaswad, Khaldoon; Araya, Mario; Avran, Alexandre; Azzalini, Lorenzo

Outcomes of chronic total occlusion (CTO) percutaneous coronary intervention (PCI) have improved because of advancements in equipment and techniques. With global collaboration and knowledge sharing, we have identified 7 common principles that are widely accepted as best practices for CTO-PCI.  1. Ischemic symptom improvement is the primary indication for CTO-PCI.  2. Dual coronary angiography and in-depth and s...


Batteries to change the world: the present and future of advanced batteries

Li, Yue; Smith, Michael John

The last 20 years have witnessed dramatic advances in the development of electrochemical power sources. Almost all the application-limiting problems have been solved and the result is that new-generation batteries are once again game-changing the electronic, mobile computing and most importantly, the plug-in electric and hybrid vehicle transport market.


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