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The inflammatory footprint of anti-breast cancer treatments and psychosocial fa...

Magda Oliveira; Susana S. Almeida; Gabriela Martins; Inês Godinho; Carlos Palmeira; Maria Emília Sousa; Lia Fernandes; Rui Medeiros


Emotional, inflammatory, and genetic factors of resilience and vulnerability to...

Susana S. Almeida; Magda Oliveira; Rui Medeiros; Marina Prista Guerra; Carmine M. Pariante; Lia Fernandes


Frailty phenotype in heart failure: A condition that transcends age

Valdiviesso, Rui; Moreira, E; Martins, S; Azevedo L; Ataide, R; Lia Fernandes; Silva Cardoso, J; Borges, Nuno

Introduction and objectives: Studies on younger frail and pre-frail subjects suffering from heart failure (HF) are scarce, except for those focusing on the critically ill. This work aims to describe differences between younger (<65 years) and older (>= 65 years) pre-frail and frail HF outpatients regarding their nutritional, functional and clinical statuses.Methods: In this cross-sectional study, a sample of 99...


Associations of medicine use and ejection fraction with the coexistence of frai...

Valdiviesso, Rui; Amaral, Teresa; Moreira, E.; Sousa-Santos, A.R.; Fernandes, M.; Aguiar, M.J.V.; Martins, S.; Azevedo, L.; Lia Fernandes

BackgroundFrailty and sarcopenia have been extensively studied in heart failure (HF) patients, but their coexistence is unknown. The aim of this work is to describe the coexistence of these conditions in a sample of HF outpatients and its association with the use of medication and left-ventricular ejection fraction.MethodsParticipants in this cross-sectional study were recruited from a HF outpatients' clinic in...


Frailty phenotype and associated nutritional factors in a sample of Portuguese ...

Valdiviesso, Rui; Azevedo L; Moreira, E; Ataíde, R; Martins, S; Lia Fernandes; Silva Cardoso, J; Borges, Nuno

Background and aim: Frailty phenotype (FP) is very common in heart failure (HF) and both syndromes worsen one another. The aim of this study is to first describe FP in a sample of Portuguese patients with HF, and to analyse its association with nutritional and clinical statuses, namely, muscle mass, obesity and functional class. Methods and results: In this cross-sectional study, a sample of 136 outpatients wit...


Anxiety in heart failure patients: its association with depression, cognition, ...

Tatiane Fidelis; Ana Paula Azzam; Andreia Nunes; Teresa Limpo; Emília Moreira; Sónia Martins; José Silva Cardoso; Lia Fernandes; São Luís Castro

Heart failure (HF) is a disabling diagnosis with an unfavorable prognosis, which is considered a worldwide public health problem and the first cause of death when compared with other cardiovascular diseases. Research showed that the relationship between psychological disorders and cardiovascular diseases increases the risk and worsens the prognosis of these diseases. Despite being the most present psychological...


Standing balance in individuals with Parkinson's disease during single and dual...

Ângela Fernandes; Tiago Coelho; Ana Vitória; Augusto Ferreira; Rubim Santos; Nuno Rocha; Lia Fernandes; João Manuel R. S. Tavares

This study aimed to examine the differences in standing balance between individuals with Parkinson's disease (PD) and subjects without PD (control group), under single and dual-task conditions. A cross-sectional study was designed using a non-probabilistic sample of 110 individuals (50 participants with PD and 60 controls) aged 50 years old and over. The individuals with PD were in the early or middle stages of...


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