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Western outcomes of circumferential endoscopic submucosal dissection for early ...

de Santiago, Enrique Rodríguez; van Tilburg, Laurelle; Deprez, Pierre H.; Pioche, Mathieu; Pouw, Roos E.; Bourke, Michael J.; Seewald, Stefan

Background and Aims: Circumferential endoscopic submucosal dissection (cESD) in the esophagus has been reported to be feasible in small Eastern case series. We assessed the outcomes of cESD in the treatment of early esophageal squamous cell carcinoma (ESCC) in Western countries. Methods: We conducted an international study at 25 referral centers in Europe and Australia using prospective databases. We included a...


X-tackling the path to closure: post-endoscopic submucosal dissection defect re...

Neves, João A. Cunha; Chaves, Jéssica; Ribeiro, Mário Dinis; Libânio, Diogo

Mucosal defect closure after endoscopic submucosal dissection (ESD) may reduce the likelihood of delayed bleeding and perforation [1]. Several devices are currently available for the closure of mucosal defects, including through-the-scope (TTS) and over-the-scope (OTS) clips, and OTS endoscopic suturing devices. However, defect closure can be technically demanding, with TTS clips typically limited to defects up...


Curative criteria for endoscopic treatment of gastric cancer

Neves, João A. Cunha; Delgado-Guillena, Pedro G.; Queirós, Patrícia; Libânio, Diogo; Rodríguez de Santiago, Enrique

Endoscopic treatment, particularly endoscopic submucosal dissection, has become the primary treatment for early gastric cancer. A comprehensive optical assessment, including white light endoscopy, image-enhanced endoscopy, and magnification, are the cornerstones for clinical staging and determining the resectability of lesions. This paper discusses factors that influence the indication for endoscopic resection ...


Outcomes of single-operator cholangioscopy-guided lithotripsy in patients with ...

Canena, Jorge; Lopes, Luís; Fernandes, João; Alexandrino, Gonçalo; Lourenço, Luís; Libânio, Diogo; Horta, David; Giestas, Sílvia; Reis, Jorge

Background and Aims: Endoscopic retrograde cholangiopancreatography is the preferred strategy for the management of biliary and pancreatic duct stones. However, difficult stones occur, and electrohydraulic (EHL) and laser lithotripsy (LL) have emerged as treatment modalities for ductal clearance. Recently, single-operator cholangioscopy was introduced, permitting the routine use of these techniques. We aimed to...


Epstein-Barr virus is absent in gastric superficial neoplastic lesions

Ribeiro, Joana; Malta, Mariana; Galaghar, Ana; Afonso, Luís Pedro; Libânio, Diogo; Medeiros, Rui; Dinis-Ribeiro, Mario; Pimentel-Nunes, Pedro

Epstein-Barr virus (EBV) has been associated with about 9% of all gastric carcinomas, but its role in gastric carcinogenesis remains unclear since there is lack of evidence of EBV presence in pre-neoplastic lesions of gastric mucosa. This study intends to determine the prevalence of EBV in gastric dysplasia and superficial neoplasia to clarify whether EBV infection is an early or late event in gastric cancer de...


Esophageal anastomotic stricturotomy: electroincision therapy with a needle knife

Fernandes, João; Libânio, Diogo; Giestas, Sílvia; Ramada, José; Martinez-Ares, David; Canena, Jorge; Lopes, Luís


Hybrid NOTES: complete endoscopic resection of the gastric wall assisted by lap...

Fernandes, João; Libânio, Diogo; Giestas, Sílvia; Araújo, Tarcísio; Ramada, José; Canena, Jorge; Lopes, Luís

[Excerpt] Laparoscopic wedge resection with a linear stapler is widely accepted in the treatment of gastric gastrointestinal stromal tumors (GISTs) [1, 2]. Although not complex [3], this procedure has some major drawbacks, namely failure in identifying the lesion, possible rupture of the capsule with the linear stapler, excessive normal tissue removal, and technical difficulties in reaching areas such as the ca...


Cholangioscopy-guided holmium laser lithotripsy of a stone trapped in a mechani...

Libânio, Diogo; Giestas, Sílvia; Martinez-Ares, David; Canena, Jorge; Lopes, Luís

Large common bile duct (CBD) stones can be removed with mechanical lithotripsy, although over-the-basket techniques such as electrohydraulic or pulsed dye laser lithotripsy can be necessary in cases of stone impaction.1 We report the case of a 42-year-old woman with a 30-mm stone in the CBD in whom mechanical lithotripsy was attempted after wide sphincterotomy. However, during the procedure, a rupture occurred ...


Endoscopic Ultrasound-Guided Biliary Drainage in Two Patients with Difficult Bi...

Libânio, Diogo; Giestas, Sílvia; Martinez-Ares, David; Ferreira, Frederico; Canena, Jorge; Certo, Manuela; Lopes, Luís

Endoscopic retrograde cholangiopancreatography is the method of choice for biliary drainage, although in some cases standard biliary access is difficult or even impossible. Endoscopic ultrasound (EUS)-guided endoluminal procedures are an alternative in these cases, although experience with these techniques is still limited.


Precut fistulotomy - widening its limits

Fernandes, João; Libânio, Diogo; Giestas, Sílvia; Ramada, José; Martinez-Ares, David; Canena, Jorge; Lopes, Luís


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