4 documents found, page 1 of 1
Early Left Ventricular Systolic Dysfunction Detected by Two-Dimensional Speckle...
Liberato, Christiane Bezerra Rocha; Olegario, Natália Bitar da Cunha; Fernandes, Virginia Oliveira; Montenegro, Ana Paula Dias RangelPurpose: Congenital generalized lipodystrophy (CGL) is a rare autosomal recessive disorder characterized by the absence of functional adipocytes resulting in ectopic lipid storage, metabolic disorders and early cardiovascular disease. Two-dimensional speckle-tracking (2D-STE) allows the detection of early abnormalities in myocardial function. We aimed to evaluate myocardial deformation in a large sample of CGL ...
Association between cardiovascular autonomic neuropathy and left ventricular hy...
Ponte, Clarisse Mourão Melo; Fernandes, Virgínia Oliveira; Liberato, Christiane Bezerra Rocha; Montenegro, Ana Paula Dias Rangel; Batista, Lívia AlineBackground: Congenital generalized lipodystrophy (CGL) is a rare disorder characterized by the absence of subcutaneous adipose tissue, severe insulin resistance, diabetes mellitus, and cardiovascular complications, including cardiac autonomic neuropathy (CAN), left ventricular hypertrophy (LVH), and atherosclerosis. The present study aimed to access the association between CAN parameters and cardiovascular abno...
Early commitment of cardiovascular autonomic modulation in Brazilian patients w...
Ponte, Clarisse Mourão Melo; Fernandes, Virgínia Oliveira; Gurgel, Maria Helane Costa; Vasconcelos, Izabella Tamira Galdino FariasBackground: Metabolic abnormalities in congenital generalized lipodystrophy (CGL) are associated with microvascular complications. However, the evaluation of different types of neuropathy in these patients, including the commitment of cardiovascular autonomic modulation, is scarce. The objective of the present study was to determine the prevalence of cardiovascular autonomic neuropathy (CAN) in patients with CG...
Estudo ecocadiográfico da função ventricular esquerda de pacientes com lipodist...
Liberato, Christiane Bezerra RochaCongenital generalized lipodystrophy (CGL) is an autosomal recessive disorder characterized by the absence of functional adipocytes and lipid stored in other tissues, including muscle and liver. Affected individuals develop severe insulin resistance, dyslipidemia, hepatic steatosis and diabetes, and usually with early cardiovascular mortality. Echocardiographic (ECHO) findings previously described in CGL used o...