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DETERMINATION OF VIRAL TROPISM BY GENOTYPING AND PHENOTYPING ASSAYS IN BRAZILIA...
Arruda, Liã Bárbara; Araújo, Marilia Ladeira de; Martinez, Maira Luccia; Gonsalez, Claudio Roberto; Duarte, Alberto José da Silva; Coakley, EoinThe clinical application of CCR5 antagonists involves first determining the coreceptor usage by the infecting viral strain. Bioinformatics programs that predict coreceptor usage could provide an alternative method to screen candidates for treatment with CCR5 antagonists, particularly in countries with limited financial resources. Thus, the present study aims to identify the best approach using bioinformatics to...
Date: 2014
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Origin: Oasisbr