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In vitro cytotoxic activity of Brazilian Middle West plant extracts

Mahmoud, Talal Suleiman; Marques, Maria Rita; Pessoa, Cláudia do Ó; Lotufo, Leticia Veras Costa; Magalhães, Hemerson Iury Ferreira

ABSTRACT - Cytotoxic activity of eight plant extracts, native from the Mid-West of Brazil comprising Cerrado, Pantanal and semideciduous forest, was evaluated for MDA-MB-435, SF-295, and HCT-8 cancer cell strains. A single 100 µg.mL-1 dose of each extract was employed with 72 h of incubation for all tests. Doxorubicin (1 µg.mL-1) was used as the positive control and the MTT method was used to detect the activit...

Date: 2012   |   Origin: Oasisbr

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