Diversos fármacos são manipulados na Farmácia Universitária. É o caso da Diacereína 50 mg, utilizada no tratamento da osteoartrose (OA), doença articular degenerativa crônica com elevada prevalência na população idosa. A OA tem um forte componente genético e, na maioria das vezes, tem na sobrecarga mecânica um iniciador do processo de lesão da cartilagem, evoluindo para um ciclo inflamatório e a degradação arti...
O Segundo Consenso de Granada define Problemas Relacionados a Medicamentos (PRM) como as situações em que o processo de uso de medicamentos cause, ou possa causar, a não obtenção do objetivo terapêutico ou o aparecimento de efeitos indesejados. A identificação de PRMs segue o princípio de necessidade, efetividade e segurança próprios da farmacoterapia, podendo ainda serem classificados como reais ou potenciais,...
There is growing interest in breeding rheas (Rhea americana) in Brazil. However, there are no data on the yeast microbiota of the gastrointestinal tract of this avian species, and the phenotypic characteristics of these yeasts are not known. Therefore, the aim of this work was to isolate Candida species from the digestive tract of rheas and to evaluate the in vitro antifungal susceptibility and secretion of pho...
This study evaluated the in vitro interaction between ciprofloxacin (CIP) and classical antifungals against Histoplasma capsulatum var. capsulatum in mycelial (n = 16) and yeast-like forms (n = 9) and Coccidioides posadasii in mycelial form (n = 16). This research was conducted through broth microdilution and macrodilution, according to Clinical Laboratory Standards Institute. Inocula were prepared to obtain fr...
This research aimed at investigating the cryoprotectant action of glucose and lactose on strains of Malassezia spp. and zygomycetes immobilised in sodium alginate. Twelve strains of Malassezia spp. (nine M. furfur, two M. globosa and one M. sympodialis) and 12 zygomycetes (five Rhizopus oryzae and seven Mucor hiemales) were immobilised in sodium alginate, within plastic beads, maintained in appropriate media co...
LIMA, Daniel Teixeira.; Cryopreservation is the method of choice in many banks of microorganisms because it leads to a situation of metabolic dormancy and consequently cultures are stable for long periods. By reducing the temperature may however be formed of ice crystals which tend to cause cell damage to cell damage in turn can be avoided by vitrification process which takes place by combining a solution with ...