5 documents found, page 1 of 1
Veneno de Bothrops erythromelas ( Amaral, 1923 ) induz apoptose em células epit...
Sousa, Fabíola Carine Monteiro de; Jorge, Antônio Rafael Coelho; Menezes, Ramon Róseo Paula Pessoa Bezerra de; Torres, Alba Fabíola CostaBothrops erythromelas is responsible for a large number of snakebite incidents in Northeastern Brazil. Previously, we showed the effects of whole B. erythromelas venom in an isolated kidney model. To continue the study with B. erythromelas venom, the present work aims to study the effects of this venom on MDCK tubular epithelial cells and assess gene expression involved in kidney injury, aiming at elucidating t...
Veneno da formiga Dinoponera quadriceps como fonte de peptídeos bioativos
Lima, Danya BandeiraAntimicrobial peptides have antibacterial, antiparasitic and antitumor properties. Dinoponera quadriceps ant venom (DqV) is rich in antimicrobial peptides called dinoponeratoxins (Dntxs) and it has antimicrobial and trypanocidal properties. Searching for novel trypanocidal and antitumor agents, we evaluated the antichagasic effect of DqV, Dntxs (sDq-3348, sDq-2561, sDq-1503, sDq-1319) and its fragment sDq-2561[...
Trypanocidal activity of mastoparan from Polybia paulista wasp venom by interac...
Chagas Vinhote, Juliana Freire; Lima, Danya Bandeira; Pessoa Bezerra de Menezes, Ramon Roseo Paula; Mello, Clarissa PerdigaoMade available in DSpace on 2018-11-28T21:36:47Z (GMT). No. of bitstreams: 0 Previous issue date: 2017-10-01; Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq); FUNCAP; Chagas disease, considered a neglected disease, is a parasitic infection caused by Trypanosoma cruzi, which is endemic throughout the world. Previously, the antimicrobial effect of Mastoparan (MP) from Polybia paulista wasp ve...
Potencial antimicrobiano e antiparasitário do veneno da Dinoponera quadriceps
Lima, Danya BandeiraAnimal toxins can be a source of molecular models for the design of new drugs. This study investigated the antimicrobial and trypanocidal potential from Dinoponera quadriceps ant venom (DqV) aiming to discover therapeutic value substances. We conducted the microdilution test, where it was determined the minimum inhibitory concentration (MIC) and Minimum Lethal Concentration (MLC) over Staphylococcus aureus ATCC...
Antimicrobial effect of Dinoponera quadriceps (Hymenoptera: Formicidae) venom a...
Lima, Danya Bandeira; Torres, Alba Fabíola Costa; Mello, Clarissa Perdigão; Menezes, Ramon Róseo Paula Pessoa Bezerra; Sampaio, Tiago LimaAims: Dinoponera quadriceps venom (DqV) was examined to evaluate the antibacterial activity and its bactericidal action mechanism against Staphylococcus aureus. Methods and Results: DqV was tested against a standard strain of methicillinsensitive Staphylococcus aureus (MSSA), Staph. aureus ATCC 6538P and two standard strains of methicillin-resistant Staphylococcus aureus (MRSA), Staph. aureus ATCC 33591 and Sta...