12 documents found, page 1 of 2
Inhibitory Effect of (-)-myrtenol alone and in combination with antifungal agen...
Cavalcanti, Bruno Bezerra; Diniz Neto, Hermes; Silva-Rocha, Walicyranison Plinio da; Lima, Edeltrudes de Oliveira; Barbosa Filho, José MariaThe aim of this study was to examine the effects of (-)-myrtenol alone and combined with antifungal agents against Candida spp. The Minimum Inhibitory Concentration (MIC) and Minimum Fungicidal Concentration of (-)-myrtenol and fluconazole against C. albicans and C. parapsilosis strains was obtained using CLSI guidelines. Combination of (-)-myrtenol with antifungal drugs was determined by checkboard test. The (...
Combined effect of Cinnamomum zeylanicum blume essential oil and nystatin on Ca...
Castro, Ricardo Dias de; Lima, Edeltrudes de Oliveira; Freires, Irlan de Almeida; Alves, Livia AraújoAbstract Introduction: The combination of a natural product and a synthetic antifungal may lead to a lower dose of each individual agent and consequent reduction of adverse effects and greater pharmacological synergism. Objective: This study investigated the antifungal activity of the essential oil (EO) from Cinnamomum zeylanicum Blume alone and combined with nystatin on Candida albicans growth and micromorphol...
Study of the antifungal potential of (r)-(+)-citronellal and its association wi...
Medeiros, Cássio Ilan Soares; Silva, Daniele de Figueredo; Pérez, Ana Luíza Alves de Lima; Almeida Filho, Geraldo Gonçalves deVulvovaginal candidiasis (VVC) is a common fungal infection that affects healthy women of all ages. At least 75% of women will develop one or more infections once during their lifetime, with 6 to 9% of those individuals developing recurrent infections. In view of this context, this study sought to evaluate the antifungal potential of the isolated (R)-(+)-citronellal [(R)-(+)-CT] and associated to therapeutic ag...
Antifungal effect of 7-hydroxycitronellal against C. Tropicalis strains: an in ...
Oliveira Filho, Abrahão Alves; Fernandes de Oliveira, Heloísa Mara Batista; Soares Medeiros, Cássio Ilan; Pessôa, Hilzeth de Luna FreireThe fungi of the genus Candida play a relevant role in the emergence of oral infections and are increasingly more frequent the cases of infections by non-albicans strains. In light of this context and the need for new alternatives to the antimicrobial therapy, the monoterpene [7-hidroxicitronelal] (7-HO) was evaluated for its antifungal effects. For the obtainment of the MIC and MFC values the broth microdiluti...
Pharmacological and toxicological analysis of two enantiomers derived from citr...
Medeiros, Cássio Ilan Soares; Silva, Daniele de Figuêredo; de Oliveira Filho, Abrahão Alves; Lima, Edeltrudes de OliveiraMonotherpenes are a class of secondary plant metabolites known to exhibit a variety of effects in different biological systems. Therefore, the aim of this study was to evaluate the pharmacological and toxicological effects of the enantiomers (R)-(+)- and (S)-(-)-citronellal in silico. Approximately 50% of the reasons that lead to failure in development of a drug are associated with the pharmacokinetic profile a...
Avaliação do potencial antimicrobiano do extrato etanólico bruto e frações da S...
Nascimento, Josefa Paula do; Costa, Danielly Albuquerque da; Lima, Edeltrudes de Oliveira; Alencar, Maria Carmem Batista de; Carmo, Egberto SantosAs leveduras do gênero Rhodotorula estão associadas a uma variedade de processos patológicos no homem, nos casos mais severos a taxa de mortalidade chega a 50%. A anfotericina B e o fluconazol são os fármacos de escolha utilizados no tratamento de infecções por Rhodotorula spp. no entanto, algumas cepas dessas leveduras já apresentam graus de resistência ao fluconazol. Por apresentarem diferentes propriedades t...
Phytoconstituents from Sidastrum micranthum (A. St.-Hil.) Fryxell (Malvaceae) a...
Gomes, Roosevelt Albuquerque; Teles, Yanna Carolina Ferreira; Pereira, Fillipe de Oliveira; Rodrigues, Luis Alberto de SousaSidastrum micranthum (A. St.-Hil.) Fryxell, a member of the Malvaceae family, is called malva preta in Brazil. As this species is commonly used to treat bronchitis, cough, and asthma, better knowledge of its chemical compounds is important. The phytochemical study of its hexane extract, using chromatographic techniques, led to isolation of six compounds: the triterpene isoarborinol, a mixture of sitosterol and ...
Composition and antimicrobial activity of essential oils from Poiretia bahiana ...
Araújo, Floricéa Magalhães; Passos, Maria das Graças V. M.; Lima, Edeltrudes de Oliveira; Roque, Nídia Franca; Guedes, Maria L. S.p. 1805-1810; Submitted by JURANDI DE SOUZA SILVA (jssufba@hotmail.com) on 2012-05-17T13:45:40Z No. of bitstreams: 1 __www.scielo.br_pdf_jbchs_v20n10_06.pdf: 2321874 bytes, checksum: d7017791261be7cb515eb86f1df2aa53 (MD5); Made available in DSpace on 2012-05-17T13:45:40Z (GMT). No. of bitstreams: 1 __www.scielo.br_pdf_jbchs_v20n10_06.pdf: 2321874 bytes, checksum: d7017791261be7cb515eb86f1df2aa53 (MD5) Previous ...
Atividade antimicrobiana "in vitro" e determinação da concentração inibitória m...
Antunes, Rossana Miranda Pessoa; Lima, Edeltrudes de Oliveira; Pereira, Maria S. V.; Camara, Celso de Amorim; Arruda, Thúlio Antunes deP. 517-524,Out/Dez.; Submitted by JURANDI DE SOUZA SILVA (jssufba@hotmail.com) on 2011-10-21T12:53:31Z No. of bitstreams: 1 a14v16n4.pdf: 232835 bytes, checksum: 09e4123cc08544d2f32a38fbd908527a (MD5); Made available in DSpace on 2011-10-21T12:53:31Z (GMT). No. of bitstreams: 1 a14v16n4.pdf: 232835 bytes, checksum: 09e4123cc08544d2f32a38fbd908527a (MD5) Previous issue date: 2006; Diante da problemática da resis...
Seasonal variation and antimicrobial activity of Myrcia myrtifolia essential oils
Cerqueira, Martins D. de; Souza Neta, Lourdes Cardoso de; Passos, Maria das Graças V. M.; Lima, Edeltrudes de Oliveira; Roque, Nídia Francap. 998-1003; Submitted by JURANDI DE SOUZA SILVA (jssufba@hotmail.com) on 2011-12-22T10:41:02Z No. of bitstreams: 1 a18v18n5.pdf: 72416 bytes, checksum: 3555e876265c62e6a9a3a6ec082624e4 (MD5); Made available in DSpace on 2011-12-22T10:41:02Z (GMT). No. of bitstreams: 1 a18v18n5.pdf: 72416 bytes, checksum: 3555e876265c62e6a9a3a6ec082624e4 (MD5) Previous issue date: 2007; Os óleos essenciais das folhas, flores e ...