6 documents found, page 1 of 1
Stanozolol induces ventricular dysfunction by decreasing phospholamban phosphor...
Andrade, Tadeu Uggere de; Dubois Fillho, Dionisio; Silva, Cristiane Lyrio da; Silva, Mirian de Almeida; Almeida, Simone Alves deStanozolol is a steroid that causes lipid deposition in LDLr-/- mice, although the mechanism by which this dyslipidemia results in cardiac dysfunction is little understood. The aim of this study was to evaluate the effect of stanozolol on cardiac contractility and the participation of myocardial phospholamban (pPLB) phosphorylation in an atherosclerosis mouse model. LDL receptor knockout mice (LDLr-/-) were fed...
A educação de farmacêuticos como ferramenta para melhoria do uso de medicamento...
Silva, Cintia Ribeiro da; Cruz, Manuela Martins; Cassaro, Karla Oliveira dos Santos; Brasil, Girlandia Alexandre; Lima, Ewelyne Miranda deO estudo objetivou avaliar o nível de conhecimento dos farmacêuticos sobre o Protocolo Clínico e Diretrizes Terapêuticas (PCDT)/Dislipidemia, antes e após treinamento, para implantação de serviços clínicos em farmácia pública de dispensação de medicamentos especializados e a percepção de usuários dislipidêmicos atendidos nesta farmácia, sobre o uso, as reações adversas e medidas de promoção da saúde, antes e ap...
Chronic treatment with juçara (Euterpe edulis) fruit pulp produces antihyperten...
Puppin, Augusto Altoé; Silva, Cristiane Lyrio da; Ronchi, Silas Nascimento; Silva, Mirian de Almeida; Lima, Ewelyne Miranda de; Oliveira, Bruno Gomes deBackground: Juçara açaí is a Brazilian berry with high anthocyanidin content and high antioxidant properties. A correlation between oxidative stress, hypertension and baroreflex impairment is known, however, no previous studies investigate the effect of juçara fruit pulp on hypertension. Aim: The aim of this study was to investigate antihypertensive effect of juçara (Euterpe edulis) fruit pulp in SHR animals, i...
Educational process on Pharmaceutical Care and Metabolic Syndrome for the imple...
Cruz, Manuela Martins; Cassaro, Karla Oliveira dos Santos; Falsoni, Raiana Maria Prucoli; Brasil, Girlandia Alexandre; Lima, Ewelyne Miranda deThis study aimed to evaluate the knowledge of pharmacists about Metabolic Syndrome (MS) and Pharmaceutical Care before and after participating in a training process for the implementation of clinical pharmacy in community pharmacies and to understand the perception of pharmacists about the teaching-learning process. This is a descriptive observational study with a quali-quatitative approach carried out with pha...
Finasteride promotes worsening of the cardiac deleterious effects of nandrolone...
Mata, Elizângela Faustino Da; Nascimento, Andrews Marques do; Lima, Ewelyne Miranda de; Kalil, Ieda Carneiro; Endringer, Denise Coutinho; Lenz, DominikMetabolism of anabolic androgenic steroids is important for its physiological effects. The aim was to investigate the effects of finasteride (a 5α-reductase inhibitor - 5αR) on cardiac and mutagenic effects promoted by ND. Male Wistar rats were separated into three groups: CONT, received the vehicles of ND and finasteride (Peanut oil+Saline); DECA group, received ND (20 mg.kg.week-1, i.m.), and DECAF received N...
Hypotensive effect and endothelium-dependent vascular action of leaves of Alpin...
Silva, Alessandra Tesch da; Lima, Ewelyne Miranda de; Caliman, Isabela Faco; Porto, Leonardo Luiz Souza; Nascimento, Andrews Marques doOs objetivos deste estudo foram avaliar o perfil químico de folhas de Alpinia purpurata K. Schum (AP), assim como a reatividade vascular e o efeito hipotensor agudo (EHA) do extrato etanólico de folhas de AP (EEAP). Avliou-se o perfil químico utilizando-se HPLC-UV, ICP-OES e quantificação colorimétrica de flavonoides e polifenóis totais. A reatividade vascular foi determinada utilizando leito mesentérico isolad...