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Microglia/Astrocytes-Glioblastoma Crosstalk: Crucial Molecular Mechanisms and M...
Matias, Diana; Balça-Silva, Joana; da Graça, Grazielle C.; Wanjiru, Caroline M.; Macharia, Lucy W.; Nascimento, Carla Pires; Roque, Natalia R.In recent years, the functions of glial cells, namely, astrocytes and microglia, have gained prominence in several diseases of the central nervous system, especially in glioblastoma (GB), the most malignant primary brain tumor that leads to poor clinical outcomes. Studies showed that microglial cells or astrocytes play a critical role in promoting GB growth. Based on the recent findings, the complex network of ...
Date: 2018
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Origin: Estudo Geral - Universidade de Coimbra