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Polymorphisms of folate pathway enzymes (Methylenetetrahydrofolate reductase an...

wo important polymorphisms of folate cycle enzymes, methylenetetrahydrofolate reductase ( MTHFR) C677T and thymidylate synthase (TS) enhancer region (TSER) 28-bp tandem repeat, are related to risk of various types of cancer, including brain tumors, although there are few studies on this subject. A case–control study of these two polymorphisms in astrocytomas of different grades was carried out using polymerase ...