3 documents found, page 1 of 1
Etiology and severity of diarrheal diseases in infants at the semiarid region o...
Lima, Aldo A. M.; Oliveira, Domingos B.; Quetz, Josiane S.; Havt, Alexandre; Prata, Mara M. G.; Lima, Ila F. N.; Soares, Alberto M.; Q. Filho, JoséBackground Diarrheal diseases are an important cause of morbidity and mortality among children in developing countries. We aimed to study the etiology and severity of diarrhea in children living in the low-income semiarid region of Brazil. Methodology This is a cross-sectional, age-matched case-control study of diarrhea in children aged 2–36 months from six cities in Brazil’s semiarid region. Clinical, epidemio...
Intestinal cell migration damage induced by enteropathogenic Escherichia coli s...
Cavalcante, Paloma A.; Prata, M. M. G.; Medeiros, Pedro Henrique Quintela Soares; Silva, A.V. Alves da; Quetz, Josiane S.Epithelial cell migration is an essential response to enteric pathogens such as enteropathogenic Escherichia coli (EPEC). This study aimed to investigate the effects of EPEC infection on intestinal epithelial cell migration in vitro, as well as the involvement of type III secretion system (T3SS) and Rho GTPases. Crypt intestinal epithelial cells (IEC-6) were infected with EPEC strains (E2348/69, DescF, and the ...
Epidemiology of enteroaggregative Escherichia coli infections and associated ou...
Rogawski, Elizabeth T.; Guerrant, Richard L.; Havt, Alexandre; Lima, Ila F. N.; Medeiros, Pedro H. Q. S.; Seidman, Jessica C.; McCormick, Benjamin J. J.Background Enteroaggregative E. coli (EAEC) have been associated with mildly inflammatory diarrhea in outbreaks and in travelers and have been increasingly recognized as enteric pathogens in young children with and without overt diarrhea. We examined the risk factors for EAEC infections and their associations with environmental enteropathy biomarkers and growth outcomes over the first two years of life in eight...