Funding: This study was supported by the National Council of Technological and Scientific Development (CNPq) and PROPESP/UFPA .; Ophir Loyola Hospital. Department of Clinical Medicine. Laboratory of Molecular Biology. Bel?m, PA, Brazil / Federal University of Cear?. Department of Medicine, Drug Research and Development Center. Laboratory of Pharmacogenetics. Fortaleza, CE, Brazil.; Ophir Loyola Hospital. Depart...