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Metástase Orbital de Neoplasia da Mama

Henriques, Adriana; Ramalho, Ana Rita; Lima, Jandira

Date: 2025   |   Origin: SPMI Case Reports

A Rare Case of Drug Induced Liver Injury Secondary to Empagliflozin

Nunes, Ana Luísa; Santos, Daniela; Figueiredo, Carolina; M. Ferreira, Diana; Lima, Jandira; Santos, Arsénio

Drug induced liver injury (DILI) is a condition with a wide clinical spectrum. The diagnosis represents a challenge not only due to the large number of known hepatotoxic products but especially when the substance involved is not known to induce liver damage. Empagliflozin is linked to several adverse effects but has not been convincingly associated to DILI. We report a case of a 70-year-old type 2 diabetic woma...


Thyroid dysfunction and amiodarone

Lima, Jandira; Carvalho, Patrícia; Molina, M. Auxiliadora; Rebelo, Marta; Dias, Patrícia; Vieira, José Diniz; Costa, José M. Nascimento

Although most patients remain clinically euthyroid, some develop amiodarone-induced hyperthyroidism (HPEAI) or hypothyroidism (HPOAI). The authors present a retrospective analysis of ten patients with amiodarone-induced thyroid dysfunction. Six patients were female and mean amiodarone intake was 17.7 months. HPOIA was more common (six patients). From all the patients with HPEAI, two had type 2, one had type 1, ...


Ehlers-Danlos syndrome type IV in association with a (c.970G>A) mutation in the...

Rebelo, Marta; Ramos, Leonor; Lima, Jandira; Vieira, J Diniz; Tavares, Purificação; Teixeira, Luísa; Matos, Albuquerque; Costa, J Nascimento

The Ehlers-Danlos syndrome type IV (EDS-IV) is a hereditary, autosomal dominant disease that causes a defect in the procollagen III synthesis, which results in a structural modification in this protein. An awareness of the disease is of vital importance for the optimal outcome, since the affected individuals have a high risk of vascular, intestinal and uterine rupture. It's a disease with great clinical variabi...

Date: 2012   |   Origin: Acta Médica Portuguesa

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