5 documents found, page 1 of 1
Phytochemical screening, antinociceptive and anti-inflammatory activities of Ch...
Lima, Gabrielle Mendes; Quintans-Júnior, Lucindo José; Thomazzi, Sara Maria; Almeida, Emyle Mayra Santana Alves; Melo, Mônica Santos deChrysopogon zizanioides (L.) Roberty, Poaceae, is a plant widely used in northeast Brazil in folk medicine for the treatment of various pathological conditions, including inflammatory pain. The present study evaluated the antinociceptive and anti-inflammatory effects of C. zizanioides essential oil (EO) in rodents. EO was further characterized by GC/MS. The major components of EO were identified as khusimol (19...
Anti-inflammatory and toxicity studies of atranorin extracted from Cladina kalb...
Melo, Marcelia Garcez Dória de; Araújo, Adriano Antunes de Souza; Serafini, Mairim Russo; Carvalho, Larissa Feitosa; Bezerra, Marília dos SantosAtranorin (ATR) is the main compound from the lichen Cladina kalbii Ahti, which grows in the arid regions of northeastern Brazil. This study was conducted to evaluate the anti-inflammatory and toxicological properties of ATR. To evaluate anti-inflammatory properties, paw edema was induced by injecting 0.1 mL of carrageenan into the subplantar region of the right hind paw of rats, and leukocyte migration was ind...
Bioassay-guided evaluation of central nervous system effects of citronellal in ...
Melo, Mônica Santos de; Souza, Marilia Trindade de Santana; Guimarães, Adriana Gibara; Barreto, Rosana de Souza SiqueiraThe central nervous system (CNS) depressant and anticonvulsant activities of citronellal (CT) were investigated in animal models. The CT in doses of 100, 200 and 400 mg/kg injected by i.p. route in mice caused a significant decrease in the motor activity of animals when compared with the control group. The highest dose of CT significantly reduced the remaining time of the animals on the Rota-rod apparatus up to...
Volatile constituents and behavioral change induced by Cymbopogon winterianus l...
Leite, Bárbara Lima Simioni; Souza, Thaís Teles de; Antoniolli, Ângelo Roberto; Guimarães, Adriana Gibara; Barreto, Rosana de Souza SiqueiraCymbopogon winterianus Jowitt (‘Java citronella’) is an important essential oil yielding aromatic grass cultivated in India and Brazil and its volatile essential oils extracted from its leaves are used in perfumery, cosmetics, pharmaceuticals and flavoring industries. However, there is no report on any psychopharmacological study of C. winterianus leaf essential oil (LEO) available to date. In this study, the p...
Amburana cearensis: uma revisão química e farmacológica
Almeida, Jackson Roberto Guedes da Silva; Guimarães, Adriana Gibara; Quintans, Jullyana de Souza Siqueira; Santos, Márcio Roberto Viana dosAmburana cearensis, popularly known as "umburana-de-cheiro" or "cumaru" is a tree widely distributed in northeastern of Brazil, its wood is used in furniture making and has considerable therapeutic properties in folk medicine. Several compounds have been isolated and identified from A. cearensis, including protocatechuic acid, coumarins, flavonoids (isokaempferide, kaempferol, afrormosin and 4’-methoxyfisetin) ...