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Use of ice cream containing probiotic an effective way to control dental caries?

Sette-de-Souza, Pedro Henrique; Amorim, Rebeca de Siqueira; Cartaxo, Rebeca de Oliveira; Silvério, Sara Isabel Cruz; Lima, L.

To perform a systematic review to assess the decrease in bacterial counts of Streptococcus mutans in patients who used ice cream enriched with probiotics. Is registered in the PROSPERO platform, by the code CRD42022371298. The databases were Scopus, Web of Science, Embase, Pubmed, Medline, and Science Direct, through a search algorithm based on the following PICO question: P-individuals systematically healthy a...


Role of genetic polymorphisms on neuroplasticity pathways in a cohort of Portug...

Santos, M.; Carvalho, S.; Lima, L.; Mota-Pereira, J.; Pimentel, P.; Correia, D.; Maia, D.; Gomes, S.; Cruz, A.; Medeiros, R.

Growing evidence suggests the implication of brain plasticity in antidepressant drug (AD) efficacy. Several authors have been pointing out the role of the BDNF-TrkB signaling pathway, including the downstream kinases Akt and ERK, and the mTOR pathway in neuroplasticity [1-3]. Furthermore, the prediction of AD response phenotypes of depressed patients treated with AD drugs remains a challenge for clinicians. Alt...


Exposure to PM2.5 and cardiovascular diseases in Portugal: the contribute of PM...

Martins, C.; Lima, L.; Gonçalves, S.; Assunção, R.; Serranheira, Florentino; Viegas, Susana

Particulate matter with a diameter of 2.5 μm or less (PM2.5) is one of the air pollutants more detrimental to human health, being responsible for around 400 000 premature deaths in Europe every year. Cardiovascular diseases (CVD) and air pollution are linked, with existing evidence of a causal relationship between exposure to particulate matter and cardiovascular morbidity and mortality. Under the scope of PMCa...


CARTS – Canopy Adjusted Real Time Spraying

Marques da Silva, J.R.; Correia, M.; Dias, A.; Serrano, J.; Nunes, P.; Rodrigues, R.; Alves, C.; Lima, L.; Tavares, F.; Carola, J.; Damas, F.

The structural characteristics of the canopy are a key consideration for improving the efficiency of the spray application process for tree crops. However, obtaining accurate data in an easy, practical, and efficient way, and in-real-time, is an important problem to be solved. The main objective of the project CARTS is to develop a sprayer prototype and the respective algorithms in order to manage variable rate...


“Who Cares?”: the acceptance of decentralized wastewater systems in regions wit...

Gómez-Román, C.; Lima, L.; Vila-Tojo, S.; Correa-Chica, A.; Lema, J.; Sabucedo, J.-M.

There is a growing interest in decentralized wastewater treatment systems, especially in regions with water scarcity problems or water management issues. This study aims to determine whether the perceived advantages and disadvantages (leading to acceptance) of decentralized wastewater plants in such regions are the same in regions where the population is not aware of these water issues. Firstly, this study syst...

Date: 2020   |   Origin: Repositório ISCTE

Revisiting the difference between instrumental and terminal values to predict (...

Oceja, L.; Stocks, E.; Heerdink, M.; Villar, S.; Salgado, S.; Carrera, P.; Arribas, M.; Bargsted, M.; Beramendi, M.; Caballero, A.; Espinosa, A.

Past research suggests that the connection between values and people's behaviour may not be as straightforward and robust as has been claimed. We propose that a more holistic and discriminative view that acknowledges the influence of a specific combination of values on specific kinds of behaviour is needed. In the current project, we test two hypotheses regarding the transcendental-change profile (TCP). First, ...

Date: 2019   |   Origin: Repositório ISCTE

Tailored virtual reality for smart physiotherapy

Postolache, O.; Teixeira, L.; Cordeiro, J.; Lima, L.; Arriaga, P.; Rodrigues, M.; Girão, P.

Remote sensing and Virtual Reality (VR) are technologies that create new development opportunities in the field of serious games with application in physiotherapy. Thus, during a physiotherapy training session expressed by a game around the remote sensing of user body motion provides measurements that can be used for objective evaluation of physical therapy outcomes. In this work is presented a serious game for...

Date: 2019   |   Origin: Repositório ISCTE

Alterações morfológicas e bioquímicas na trissomia 21

Reis, A.; Azevedo, S.; Lebre, A.; Valente, E.; Lima, L.; Cunha, A.

Introdução: A Trissomia 21 (T21) é a aneuploidia mais comum, apresentando uma prevalência de 1/670 nascimentos. É a principal causa de défice intelectual moderado a grave, e está associada a diversas anomalias congénitas, sendo as malformações cardiovasculares as mais frequentes. O objetivo deste trabalho é caracterizar as alterações morfológicas e bioquímicas nos casos de T21. Material e Métodos: Estudo prospe...


Influence of Il-18 genetic polymorphisms in antidepressant treatment phenotypes

Santos, Marlene; Carvalho, S.; Lima, L.; Mota-Pereira, J.; Pimentel, P.; Maia, D.; Correia, D.; Gomes, S.; Cruz, Agostinho; Medeiros, R.

Recent studies suggested that immune activation and cytokines might be involved in depression. The proinflammatory cytokine interleukin-18 (IL-18) is less reported in depression but is still relevant since it is expressed in the brain and serum levels of IL-18 have been found to be increased in patients with moderate to severe depression. Therefore, it seems reasonable that IL-18 promoter SNPs may have an effec...


Doença Hemolítica Perinatal — Caso Clínico

Gonçalves, S.; Schimt, D.; Garcia, S.; Soares, P.; Nogueira, R.; Lima, L.; Alexandrino, A. M.

A doença hemolítica perinatal resulta da passagem placentária de anticorpos do tipo IgG contra antigénios eritrocitários fetais, dando origem a hemólise. A incompatibilidade Rh(D) é a responsável por cerca de 94% casos. As incompatibilidades por antigénios atípicos (anti-c, anti-Kell) apesar de raras, dão origem a quadros graves. Os autores apresentam um caso clínico de isoimunização anti-c num prematuro, I° fi...


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