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Epidemiological and Clinical Aspects of Cutaneous and Mucosal Leishmaniases in ...

Rocha, R; Conceição, C; Gonçalves, L; Carvalho, AC; Maia, A; Martins, A; Carujo, A; Maio, A; Forra, C; Melita, C; Couto, D; Fernandes, D; Pereira, D

Leishmania infantum, a zoonotic vector-born parasite, is endemic in the Mediterranean region, presenting mostly as visceral (VL), but also as cutaneous (CL) and mucosal leishmaniasis (ML). This study aimed to describe the epidemiological and clinical aspects of the CL and ML cases diagnosed in mainland Portugal between 2010 and 2020. Collaboration was requested from every hospital of the Portuguese National Hea...

Date: 2024   |   Origin: Hospital de Cascais

Epidemiological and Clinical Aspects of Cutaneous and Mucosal Leishmaniases in ...

Rocha, R; Conceição, C; Gonçalves, L; Carvalho, AC; Maia, A; Martins, A; Carujo, A; Maio, A; Forra, C; Melita, C; Couto, D; Fernandes, D; Pereira, D

Leishmania infantum, a zoonotic vector-born parasite, is endemic in the Mediterranean region, presenting mostly as visceral (VL), but also as cutaneous (CL) and mucosal leishmaniasis (ML). This study aimed to describe the epidemiological and clinical aspects of the CL and ML cases diagnosed in mainland Portugal between 2010 and 2020. Collaboration was requested from every hospital of the Portuguese National Hea...

Date: 2024   |   Origin: Hospital de Cascais


Graphene-Based Coating to Mitigate Biofilm Development in Marine Environments

Sousa-Cardoso, F; Rita Teixeira dos Santos; Campos, AF; Lima, M; Luciana Gomes; Soares, OSGP; Filipe Mergulhão

Due to its several economic and ecological consequences, biofouling is a widely recognized concern in the marine sector. The search for non-biocide-release antifouling coatings has been on the rise, with carbon-nanocoated surfaces showing promising activity. This work aimed to study the impact of pristine graphene nanoplatelets (GNP) on biofilm development through the representative marine bacteria Cobetia mari...


The Use of 3D Optical Coherence Tomography to Analyze the Architecture of Cyano...

Maria João Romeu; Lima, M; Luciana Gomes; de Jong, ED; Morais, J; Vitor Vasconcelos; Pereira, MFR; Soares, OSGP; Sjollema, J; Filipe Mergulhão

The development of environmentally friendly antifouling strategies for marine applications is of paramount importance, and the fabrication of innovative nanocomposite coatings is a promising approach. Moreover, since Optical Coherence Tomography (OCT) is a powerful imaging technique in biofilm science, the improvement of its analytical power is required to better evaluate the biofilm structure under different s...


Assessment of the Antibiofilm Performance of Chitosan-Based Surfaces in Marine ...

Lima, M; Luciana Gomes; Teixeira-Santos, R; Romeu, MJ; Valcarcel, J; Vazquez, JA; Cerqueira, MA; Pastrana, L; Bourbon, AI; de Jong, ED; Sjollema, J

Marine biofouling is a natural process often associated with biofilm formation on submerged surfaces, creating a massive economic and ecological burden. Although several antifouling paints have been used to prevent biofouling, growing ecological concerns emphasize the need to develop new and environmentally friendly antifouling approaches such as bio-based coatings. Chitosan (CS) is a natural polymer that has b...


With or Without You: Beneficial and Detrimental Associations Between Companion ...

Lima, M; Mateus, TL; Silva, K

It has been proposed that companion animals, and dogs in particular, may be helpful during the COVID-19 pandemic, notably for psychological adjustment. The present study addressed this idea in a sample of 509 Portuguese individuals exposed to a national lockdown. Linear regression analyses were performed to test for associations between having lived with a dog during that phase and experienced levels of anxiety...


The impact of an 8-week Pilates-based physical training program on functional m...

Lima, M; Silva, B; Rocha-Rodrigues, S; Bezerra, P

Study aim: This study aimed to evaluate the effects of a Pilates-based training program on functional mobility and strength in community-dwelling adults over 70 years old. Material and methods: Twenty community-dwelling elderly subjects were recruited and randomly assigned to control (C = 10) or Pilates training (PT = 10) groups for 8 weeks (2 times/week). Anthropometric, strength, cardiorespiratory fitness, fu...


Genome-wide association study identifies genetic factors that modify age at ons...

Akçimen, F; Martins, S; Liao, C; Bourassa, CV; Catoire, H; Nicholson, GA; Riess, O; Raposo, M; França, MC; Vasconcelos, J; Lima, M; Lopes-Cendes, I

Machado-Joseph disease (MJD/SCA3) is the most common form of dominantly inherited ataxia worldwide. The disorder is caused by an expanded CAG repeat in the ATXN3 gene. Past studies have revealed that the length of the expansion partly explains the disease age at onset (AO) variability of MJD, which is confirmed in this study (Pearson's correlation coefficient R2 = 0.62). Using a total of 786 MJD patients from f...


Cytomegalovirus Pseudotumor of the Colon in an HIV Patient

Lima, M; Matos, AP; Ramalho, M

Cytomegalovirus (CMV) is the most common cause of severe opportunistic viral disease among patients with acquired immunodeficiency syndrome, and colitis is the most frequent manifestation of CMV infection. Nevertheless, the development of a colonic pseudotumor is a rare benign entity that can be easily misdiagnosed as a colonic neoplasm if the radiologist is not aware of this condition. We present a case of a 4...


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