16 documents found, page 1 of 2
Effects of hyperleptinemia in rat saliva composition, histology and ultrastruct...
Lamy, Elsa; Neves, S; Ferreira, J; Rodrigues, Lénia; da Costa, G; Cordeiro, C; Fialho, Luisa; Lima, Mónica; Costa, Ana R.; Antunes, Célia M.OBJECTIVE: To study the effect of the satiety hormone, leptin, in saliva proteome and salivary gland histology and ultrastructure. DESIGN: Increases in blood leptin levels were induced through mini-pump infusion in male Wistar rats, during a period of 7 days. Saliva was collected before and at the end of the experimental period, for proteomic analysis, and major salivary glands were collected, at the end, for b...
Pharmacological and Toxicological Studies of Essential Oil of Lavandula stoecha...
Arantes, Sílvia; Candeias, Fátima; Lopes, Orlando; Lima, Mónica; Pereira, Marízia; Tinoco, Teresa; Cruz-Morais, Júlio; Martins, M. RosárioThe present study was carried out to evaluate the chemical and pharmacological properties of essential oil (EO) of Lavandula stoechas L. subsp. luisieri that is a spontaneous shrub widespread in Alentejo (Portugal). Oxygenated monoterpenes, as 1,8-cineole, lavandulol and necrodane derivatives are the main components of essential oil. It revealed important antioxidant activity with high ability to inhibit the li...
Biomarker evaluation and toxicological study of essential oils of Foeniculum vu...
Piçarra, Andreia; Arantes, Silvia; Candeias, Fátima; Lopes, Orlando; Lima, Mónica; Tinoco, Teresa; Martins, RosárioThe aim of this study was to evaluate the toxicological properties of EOs of F. vulgare and C. nepeta, widespread in Mediterranean agrosilvopastoral systems and often used as food condiments in Alentejo. EOs were obtained from aerial part of plants by hydrodistillation and chemical composition was evaluated by GC-FID. Toxicity of essential oils was evaluated by the estimation of LC50 in brine shrimp and LD50 in...
Biomarkers and toxicological evaluation of Lavandula spp. essential oils
Arantes, Silvia; Candeias, M. Fátima; Piçarra, Andreia; Lopes, Orlando; Lima, Mónica; Pereira, Marizia; Cruz-Morais, Júlio; Martins, M. RosárioLavenders belong to the family Labiatae and are one of the most popular aromatic plants widely used in food industry, perfumery and pharmaceutical preparations. Their oils are traditionally believed to be antibacterial, antifungal, carminative, sedative, antidepressive, disinfectant, and effective for burns and insect bites [1]. Previous studies have shown that the essentials oils of Lavandula stoechas subsp. l...
Toxicological and pharmacological evaluation of the essential oil and aqueous e...
Arantes, Silvia; Candeias, M. Fátima; Pereira, Marizia; Lopes, Orlando; Lima, Mónica; Martins, M. RosárioLavenders belong to the family Labiatae and represent some of the most popular medicinal plants extensively used in aromatherapy. In this study, we selected Lavandula stoechas L. subsp. luisieri (Rozeira) Rozeira, endemic of Portugal, collected in Évora (Alentejo). The aim of this study was to evaluate the acute toxicity and the analgesic and anti-inflammatory activities of the essential oil and aqueous extract...
Variations in salivary function in a rodent model of pre-diabetes
Rodrigues, Lénia; Mouta, Raquel; Barra, Cátia; Costa, Ana R; Silva, Fernando C; Lopes, Orlando; Lima, Mónica; Lamy, ElsaDiabetes is a widespread disease representing an enormous part of the total health costs. An early diagnostic could be of extremely importance both for the understanding and prevention of this pathology. Saliva is a fluid with increasing interest as a source of biomarkers for disease diagnostic and saliva protein composition changes have already been reported for diabetic individuals. However, the studies were ...
Avaliação farmacológica e toxicológica do óleo essencial e extrato aquoso deLav...
Arantes, Silvia; Candeias, M. Fátima; Pereira, Marízia; Lopes, Orlando; Lima, Mónica; Cruz Morais, Júlio; Martins, M. RosárioAs plantas do género Lavandula L. pertencentes à família Labiatae, são plantas aromáticas de grande importância económica muito usadas na medicina tradicional. Neste estudo, foi selecionada uma espécie natural do Alentejo, Lavandula stoechas L. subsps. luisieri (Rozeira) Rozeira, vulgarmente conhecida por rosmaninho, recolhida de uma mancha da Herdade da Mitra (Évora) O objetivo deste estudo foi avaliar as ativ...
Effects of carbon source, carbon concentration and culture conditions on in vit...
Zavattieri, Maria Amely; Lima, Mónica; Sobral, Virginia; Oliveira, Paulo Guilherme de; Costa, Alexandra Rosa daIn stone pine (Pinus pinea L.), clonal propagation via adventitious shoot formation from cotyledons has been reported before but rooting of these shoots is poor. The number of rooted shoots had low frequency limiting the used of micropropagation protocols as a choice for mass propagation of superior genotypes. Therefore the main objective of the present work was to increase the number and quality of roots per s...
Biodegradation assessment of a 16th century fresco from Southern Portugal
Martins, M. Rosário; Fialho, Susana; Lima, Mónica; Tavares, Deolinda; Mirão, José; Valadas, Sara; Candeias, António E.This work reports the study of the frescoes from the Casa de Fresco dos Sanches Baena in Vila Viçosa (Southeast Portugal) to allow their material characterisation, to identify the different populations of microorganisms and to assess their role in the deterioration of these paintings.
Diagnóstico da biodeterioração por fungos e bactérias nas pinturas murais da Ca...
Martins, M. Rosário; Fialho, Susana; Lima, Mónica; Valadas, Sara; Candeias, António; Mirão, J.; Silva, A. S.; Tavares, Deolinda; Botto, M.A Casa de Fresco de Sanches Baena, situada em Vila Viçosa (Sudeste de Portugal), é uma pequena construção semi-subterrânea, de planta quadrangular,anexa à nora do antigo Palácio dos Sanches Baena. Os frescos que cobrem a sua abóbada e paredes apresentam cenas mitológicas ricas conjugadas com anjos musicais, conchas, porcelana e outros elementos decorativos, os quais fazem dela um exemplar especialmente rico e i...