Submitted by ROBERTO PAULO CORREIA DE ARAÚJO (ppgorgsistem@ufba.br) on 2017-06-05T16:30:20Z No. of bitstreams: 1 14_v.9_2.pdf: 221781 bytes, checksum: d402fed1f78e9ac81bb6a9c54c8a794e (MD5); Made available in DSpace on 2017-06-05T16:30:20Z (GMT). No. of bitstreams: 1 14_v.9_2.pdf: 221781 bytes, checksum: d402fed1f78e9ac81bb6a9c54c8a794e (MD5) Previous issue date: 2010-05; O Vírus Esptein-Barr (EBV) é amplamente...
The oral cancer represents a serious world public health problem. The oral squamous cell carcinomas (OSCC) account for up to 94% of the tumors of this anatomic site. The molecular mechanisms involved in the genesis and progression are still not well elucidated. Some evidences have suggested the involvement of viruses in this process. Also, these tumors still lack of reliable markers to determine the aggressiven...
The human papillomavirus (HPV) is an epitheliotropic agent whose high-risk genotypes have a well-established link with the development of cervical cancer. Although the relation of HPV to the oral squamous cell carcinoma (OSCC) has been studied since the beginning of the 1980s, its role in the oral carcinogenesis and the probable underlying molecular mechanisms are still not fully elucidated. We performed a syst...
Introdução: o Papilomavírus Humano (HPV) é um agente epiteliotrópico que apresenta mais de 100 genótipos. d estes, alguns são considerados de alto risco devido ao potencial para induzir o surgimento de lesões malignas, como o carcinoma cervical, cujo percentual de associação com o referido vírus é de aproximadamente 90%. n as células infectadas, duas proteínas virais desempenham papel fundamental na tumorigênes...
Submitted by Guilherme Lemeszenski (guilherme@nead.unesp.br) on 2013-08-22T18:41:32Z No. of bitstreams: 1 S1517-83822012000100048.pdf: 2059404 bytes, checksum: b3127f4b88eb3b11b22ad3258bbd6163 (MD5); Made available in DSpace on 2013-08-22T18:41:33Z (GMT). No. of bitstreams: 1 S1517-83822012000100048.pdf: 2059404 bytes, checksum: b3127f4b88eb3b11b22ad3258bbd6163 (MD5) Previous issue date: 2012-03-01; Made availa...
Submitted by Guilherme Lemeszenski (guilherme@nead.unesp.br) on 2013-08-22T18:43:23Z No. of bitstreams: 1 S1676-24442011000200013.pdf: 256846 bytes, checksum: f38a5b211a723314f6d34831697e0848 (MD5); Made available in DSpace on 2013-08-22T18:43:23Z (GMT). No. of bitstreams: 1 S1676-24442011000200013.pdf: 256846 bytes, checksum: f38a5b211a723314f6d34831697e0848 (MD5) Previous issue date: 2011-04-01; Made availabl...
ackground: The association between Helicobacter pylori gene diversity and gastric cancer has been poorly reported, although it is one of the important ways to explain the gastric pathogenesis. The aim of this study was to investigate the frequency of cag E and vir B11 genes in H. pylori isolated from patients with gastric cancer and to analyze the histology profiles. Materials and methods: The presence of H. py...
AIM: To investigate the interrelationship between H pylori and Epstein-Barr virus (EBV) infection in the gastric carcinogenesis having in focus the p53 mutation and the c-Myc, Bcl-2 and Bax expression. METHODS: seventy-one gastric carcinoma tissues were assessed by polymerase chain reaction (PCR) for H pylori and in situ hybridization for EBV. c-Myc, Bcl-2 and Bax expression were detected by immunohistochemistr...
The Epstein-Barr virus (EBV) has been related to the tumorigenesis of the gastric carcinomas, varying from 1.3-19.3% according to the studied population. Several studies have demonstrated strong evidences of its relation in this process, such as the monoclonality of the viral genome and its the presence in almost all tumor cells. However, most of the mechanisms used by the virus to control this process are stil...