Dietary fiber intake plays an important role in the prevention of obesity. This study aimed at investigating the effect of cashew fiber without low molecular weight compounds (CABwc) on obesity prevention and metabolomics in a murine model of diet-induced obesity. Mice were fed a chow diet (CD), a high-fat diet (HFD) or a high-fat diet supplemented with CABwc (10%) (HFD-CABwc) for 15 weeks. The body weight, abd...
Non-alcoholic fatty liver disease (NAFLD) is a clinical-pathological condition defined by the abnormal accumulation of triglycerides in hepatocytes, commonly called hepatic steatosis (HS). Currently, only pioglitazone, an insulin sensitizing agent, and vitamin E as an antioxidant are recommended for the treatment of non-alcoholic hepatic steatosis by international guidelines. In the search for new therapeutic o...