4 documents found, page 1 of 1
Dectin-1-Mediated Production of Pro-Inflammatory Cytokines Induced by Yeast β-G...
Pedro, ARV; Lima, T; Fróis-Martins, R; Leal, B; Ramos, IC; Martins, EG; Cabrita, ARJ; Fonseca, AJM; Maia, MRG; Vilanova, M; Correia, AYeast-derived products containing β-glucans have long been used as feed supplements in domesticated animals in an attempt to increase immunity. β-glucans are mainly recognized by the cell surface receptor CLEC7A, also designated Dectin-1. Although the immune mechanisms elicited through Dectin-1 activation have been studied in detail in mice and humans, they are poorly understood in other species. Here, we evalu...
Siderophore-Mediated Iron Acquisition Plays a Critical Role in Biofilm Formatio...
Oliveira, F; Lima, T; Correia, A; Silva, AM; Soares, C; Morais, S; Weißelberg, S; Vilanova, M; Rohde, H; Cerca, NIron acquisition through siderophores, a class of small, potent iron-chelating organic molecules, is a widely spread strategy among pathogens to survive in the iron-restricted environment found in the host. Although these molecules have been implicated in the pathogenesis of several species, there is currently no comprehensive study addressing siderophore production in Staphylococcus epidermidis. Staphylococcus...
Understanding the Lipid and Protein Corona Formation on Different Sized Polymer...
Lima, T; Bernfur, K; Vilanova, M; Cedervall, TWhen in contact with biological fluids, nanoparticles dynamically absorb biomolecules like proteins and lipids onto their surface, forming a “corona”. This biocorona is a dynamic and complex structure that determines how host cells respond to nanoparticles. Despite the common use of mouse models in pre-clinical and toxicological experiments, the impact of corona formed in mouse serum on the biophysical and biol...
Traumatic middle cerebral artery aneurysm secondary to a gunshot wound.
Santos, G; Lima, T; Pereira, S; Macahdo, ETraumatic intracranial aneurysms are rare lesions, accounting for less than 1% of all intracranial aneurysms. Formation of these lesions after a penetrating missile wound is very unusual, and diagnosis can be difficult due to the presence of associated lesions. In this article, we report a case of a woman who developed a middle cerebral artery aneurysm after a gunshot wound, and discuss potential pitfalls found...