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New Heteroleptic RuII/Diphosphine Complexes with Cytotoxicity against Human Bre...

Lima,Benedicto A. V.; Corrêa,Rodrigo S.; Graminha,Angélica E.; Varela Júnior,Jaldyr J. G.; Silva,Albérico B. F. da; Ellena,Javier; Silva,Thales E. M.

The preparation, characterization, theoretical calculations and biological application of four RuII complexes with 2-picolinate (pic), 2,2’-bipyridine (bipy) and P-P as ligands [P-P = 1,1-bis(diphenylphosphino)methane (dppm-1), 1,2-bis(diphenylphosphino)ethane (dppe-2), 1,3-bis(diphenylphosphino)propane (dppp-3) or 1,1’-bis(diphenylphosphino)ferrocene (dppf-4)], is here presented. The complexes 1-4, with genera...

Date: 2020   |   Origin: Oasisbr

Anti-Mycobacterium tuberculosis and Cytotoxicity Activities of Ruthenium(II)/ B...

Lima,Benedicto A. V.; Corrêa,Rodrigo S.; Graminha,Angelica E.; Kuznetsov,Aleksey; Ellena,Javier; Pavan,Fernando R.; Leite,Clarice Q. F.

The [Ru(Spym)(bipy)(P–P)]PF6, [Spym = pyrimidine-2-thiolate anion; P–P = 1,2-bis(diphenylphosphino)ethane, 1,3-bis(diphenylphosphino)propane and 1,1'-bis(diphenylphosphino)ferrocene] complexes were synthesized and characterized by spectroscopic, electrochemical and elemental analysis, and by X-ray crystallography. The minimal inhibitory concentration (MIC) of the compounds against Mycobacterium tuberculosis and...

Date: 2016   |   Origin: Oasisbr

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