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Strong SOD2 expression and HPV-16/18 positivity are independent events in cervi...

Rabelo-Santos, Silvia Helena; Termini, Lara; Boccardo, Enrique; Derchain, Sophie; Longatto, Adhemar; Andreoli, Maria Antonieta; Costa, Maria Cecília

It is well known that persistent infection with high-risk HPV (hr-HPV), mostly HPV-16 and 18, is the main cause of cervical cancer development. Manganese superoxide dismutase (MnSOD or SOD2) are highly expressed in different neoplasia. The present study investigated SOD2 protein expression and the presence of hr-HPV types in 297 cervical samples including non-neoplastic tissue, cervical intraepithelial neoplasi...

Date: 2018   |   Origin: RepositóriUM - Universidade do Minho
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