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Global Consensus Recommendations for Metabolic Dysfunction-Associated Steatotic...
Younossi, Zobair M.; Zelber-Sagi, Shira; Lazarus, Jeffrey V.; Wong, Vincent Wai Sun; Yilmaz, Yusuf; Duseja, Ajay; Eguchi, Yuichiro; Castera, LaurentFunding Information: Funding This study was partially supported by the Global NASH/MASH Council , Center for Outcomes Research in Liver Diseases , Washington, DC, and the Beatty Liver and Obesity Research Fund, Inova Health System, Falls Church, VA. The study was also supported by an unrestricted educational grant from Madrigal Pharmaceuticals. This partial sponsor had no input in study design, performance of t...
Lipidomic profiling unveils sex differences in diabetes risk
Pina, Ana; Meneses, Maria João; Carli, Fabrizia; RT, Ribeiro; Gardete-Correia, Luís; Boavida, Ana; RAPOSO, JOÃO; Gastaldelli, Amalia; P Macedo, MPublisher Copyright: © 2025 The Author(s). European Journal of Clinical Investigation published by John Wiley & Sons Ltd on behalf of Stichting European Society for Clinical Investigation Journal Foundation.; Aims/Hypothesis: Type 2 diabetes is a multifactorial condition whose greatest impact comes from its complications. We hypothesized that distinct insulin-derived mechanisms and lipid profiles discriminate s...
A global action agenda for turning the tide on fatty liver disease
Lazarus, Jeffrey V.; Mark, Henry E.; Allen, Alina M.; Arab, Juan Pablo; Carrieri, Patrizia; Noureddin, Mazen; Alazawi, William; Alkhouri, NaimFunding Information: the Liver (CASL), Duke University, European Association for the Study of the Liver (EASL), Gastroenterology Updates, IBD, Liver Disease (GUILD), Houston Methodist, International Liver Transplantation Society (ILTS), Pakistan Society for the Study of Liver Disease (PSSLD), and University of Alabama, Birmingham (UAB). She received grants from Durect Corp, Genentech-Roche, Gilead, GlaxoSmithKl...
Insights into circulating CEACAM1 in insulin clearance and disease progression
Patarrão, Rita S.; Meneses, Maria João; Ghadieh, Hilda E.; Herrera, Laura; Duarte, Sérgio; Ribeiro, Rogério T.; Raposo, João F.; Schmitt, VerenaFunding Information: The authors thank the study participants for commitment and loyalty. The authors would like to acknowledge the guidance of the late PD Dr. Bernhard B. Singer, PhD and from Verena Schmitt, PhD from the Universit\u00E4tsklinikum, Essen, Germany for their guidance on setting up the ELISA analysis of circulating CEACAM1 levels. This study was supported by \u201CFunda\u00E7\u00E3o para a Ci\u00E...
The Effects of Long-Term High Fat and/or High Sugar Feeding on Sources of Postp...
Reis-Costa, Ana; Belew, Getachew D.; Viegas, Ivan; Tavares, Ludgero C.; Meneses, Maria João; Patrício, Bárbara; Gastaldelli, Amalia; Macedo, Maria PaulaFunding Information: The authors acknowledge financial support from the Portuguese Foundation for Science and Technology (research grant FCT-FEDER-02/SAICT/2017/028147 and UIDB/Multi/04462/2020) and the Portuguese Society of Diabetology (GIFT-2020). Structural funding for the Center for Neurosciences and Cell Biology and the UC-NMR facility is supported in part by FEDER\u2014European Regional Development Fund t...
Gut-pancreas-liver axis as a target for treatment of nafld/nash
Svegliati-Baroni, Gianluca; Patrício, Bárbara; Lioci, Gessica; Macedo, Maria Paula; Gastaldelli, AmaliaNon-alcoholic fatty liver disease (NAFLD) represents the most common form of chronic liver disease worldwide. Due to its association with obesity and diabetes and the fall in hepatitis C virus morbidity, cirrhosis in NAFLD is becoming the most frequent indication to liver transplantation, but the pathogenetic mechanisms are still not completely understood. The so-called gut-liver axis has gained enormous intere...