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RADIATION-ASSOCIATED CUTANEOUS BREAST ANGIOSARCOMA – 12 YEARS ANALYSIS OF A RAD...

Roda, Domingos; Melo, Gilberto; Figueiredo, Paulo

Introduction: The radiation induced (RI) cutaneous angiosarcoma (CAS) in the context of the treatment of breast cancer is a rare but extremely aggressive tumor.Aim: The aim of this study was to review and present the clinical cases of RI CAS of a Radiotherapy (RT) service of, by analyzing the clinical in the last 12 years.Material and Methods: We retrospectively analyzed the clinical cases of primary atypical v...


Estratégia preventiva da mucosite oral em doentes com tumores de cabeça e pesco...

Mousinho, Filipa; Costa Ferreira, Brigida; Khouri, Leila; Guardado, Maria João; Vale Marques, Rui; Rodrigues, Joana M.C.; Melo, Gilberto

A mucosite oral é uma consequência frequente no tratamento de doentes oncológicos, nomeadamente de cabeça e pescoço. Refere-se a lesões eritematosas e ulcerativas da mucosa oral em doentes submetidos a radioterapia e/ou quimioterapia. Estas lesões são muitas vezes dolorosas e podem comprometer a nutrição, a hidratação, a higiene oral e ainda aumentar o risco de infecção sistémica. Infecções associadas a mucosit...


Secondary Hypothyroidism after Cervical Irradiation: Systematic Evaluation of T...

Gonçalves, Sara Monteiro; Ferreira, Brigida da Costa; Guardado, Maria João; Marques, Rui; Serra, Tânia; Serra, Maria João; Roda, Domingos

Introduction: Sometimes Thyroid dysfunction is an underestimated consequence of radiation exposure. The underlying mechanism is not clearly understood, but it is likely to be multifactorial. As so, the specific risk factors associated with the development of secondary radiotherapy hypothyroidism remain undefined. The direct irradiation of the thyroid gland may result more frequently in hypothyroidism. This is a...

Date: 2014   |   Origin: Acta Médica Portuguesa

Hypofractionation in Locally Advanced Breast Cancer: “Flash” Scheme

Padilha, Marisa; Gonçalves, Sara; Fardilha, Carlos; Melo, Gilberto; Miranda, Cristina; Alves, Paula

Introduction: Breast cancer is a major cause of death in our country. The Department of Radiation Oncology of Portuguese Institute of Oncology in Coimbra are using a scheme of hypofraccionation called “Flash” as a treatment option for elderly patients or low performance status, with locally advanced breast cancer, or with stage IIb or IV, as a neoadjuvante or palliative aim. Objectives: Evaluation of the therap...

Date: 2013   |   Origin: Acta Médica Portuguesa

Neoadjuvant Radiotherapy and Hormonotherapy in Locally Advanced Breast Cancer: ...

Padilha, Marisa; Henriques, Mónica; Guardado, Maria João; Miranda, Cristina; Melo, Gilberto; Alves, Paula

Introduction: Breast cancer is a health problem of great magnitude. In recent years we have seen an increasing incidence anddecreasing mortality from this disease due to implementation of campaigns for early diagnosis and the effectiveness of existing treatments.For more than a century that we know the evidence that growth and development of some tumours depends in part on hormonalstimuli, and the purpose of ho...

Date: 2013   |   Origin: Acta Médica Portuguesa

Cancro Ginecológico – consensos nacionais 2013

Pregal, Alexandra; Sofia, Alexandra Rico; Petiz, Almerinda; Félix, Ana; Jorge, Ana Francisca; Costa, Ana Marta; Lagoa, António; Alves, Boaventura


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