40 documents found, page 1 of 4
Aging whole blood transcriptome reveals candidate genes for SARS-CoV-2-related ...
de Almeida Chuffa, Luiz Gustavo [UNESP]; Freire, Paula Paccielli; dos Santos Souza, Jeferson [UNESP]; de Mello, Mariana Costa [UNESP]Made available in DSpace on 2022-04-29T08:46:05Z (GMT). No. of bitstreams: 0 Previous issue date: 2022-02-01; Abstract: The risk of severe COVID-19 increases with age as older patients are at highest risk. Thus, there is an urgent need to identify how severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) interacts with blood components during aging. We investigated the whole blood transcriptome from the ...
Preventive training does not interfere with mRNA-encoding myosin and collagen e...
Mariano, Thaoan Bruno; De Souza Castilho, Anthony César; De Almeida Sabela, Ana Karenina Dias; De Oliveira, André CasanovaMade available in DSpace on 2022-04-29T08:32:48Z (GMT). No. of bitstreams: 0 Previous issue date: 2021-09-01; Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP); To gain insight on the impact of preventive exercise during pulmonary arterial hypertension (PAH), we evaluated the gene expression of myosins and gene-encoding proteins associated with the extracellular matrix remodeling of right hypertroph...
MiR-125a-3p and miR-320b differentially expressed in patients with chronic myel...
Martins, Juliana R. B. [UNESP]; Moraes, Leonardo N. [UNESP]; Cury, Sarah S. [UNESP]; Capannacci, Juliana [UNESP]; Carvalho, Robson Francisco [UNESP]Made available in DSpace on 2022-04-29T08:33:15Z (GMT). No. of bitstreams: 0 Previous issue date: 2021-10-01; Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP); Chronic myeloid leukemia (CML), a hematopoietic neoplasm arising from the fusion of BCR (breakpoint cluster region) gene on chromosome 22 to the ABL (Abelson leukemia virus) gene on chromosome 9 (BCR-ABL1 oncogene), originates from a small p...
An insight on the impact of teleost whole genome duplication on the regulation ...
Duran, Bruno Oliveira Silva [UNESP]; de la Serrana, Daniel Garcia; Zanella, Bruna Tereza Thomazini [UNESP]; Perez, Erika Stefani [UNESP]Made available in DSpace on 2022-05-01T06:31:27Z (GMT). No. of bitstreams: 0 Previous issue date: 2021-07-01; Fish muscle growth is a complex process regulated by multiple pathways, resulting on the net accumulation of proteins and the activation of myogenic progenitor cells. Around 350–320 million years ago, teleost fish went through a specific whole genome duplication (WGD) that expanded the existent gene rep...
TLR4 deficiency upregulates TLR9 expression and enhances irinotecan-related int...
Wong, Deysi Viviana Tenazoa; Holanda, Renata Brito Falcão; Cajado, Aurilene Gomes; Bandeira, Alessandro Maia; Pereira, Jorge Fernando BessaMade available in DSpace on 2022-05-01T07:58:47Z (GMT). No. of bitstreams: 0 Previous issue date: 2021-10-01; Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq); Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES); Fundação Cearense de Apoio ao Desenvolvimento Científico e Tecnológico; Background and purpose: Severe diarrhoea, a common gastrointestinal manifestation of anticanc...
Maternal protein restriction changes structural and metabolic gene expression i...
Valente, Jéssica Silvino [UNESP]; Perez, Érika Stefani [UNESP]; Zanella, Bruna Tereza Thomazini [UNESP]; de Paula, Tassiana Gutierrez [UNESP]Made available in DSpace on 2022-05-01T09:47:28Z (GMT). No. of bitstreams: 0 Previous issue date: 2021-08-01; Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP); Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES); Maternal protein restriction affects postnatal skeletal muscle physiology with impacts that last through senility. To investigate the morphological and molecular characteri...
Drug repositioning based on the reversal of gene expression signatures identifi...
Carvalho, Robson Francisco [UNESP]; Canto, Luisa Matos Do; Cury, Sarah Santiloni [UNESP]; Hansen, Torben Frøstrup; Jensen, Lars HenrikMade available in DSpace on 2022-05-01T09:47:31Z (GMT). No. of bitstreams: 0 Previous issue date: 2021-11-01; National Cancer Institute; National Heart, Lung, and Blood Institute; National Institute on Drug Abuse; National Institute of Mental Health; Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES); Rectal cancer is a common disease with high mortality rates and limited therapeutic options. H...
Multidimensional single-nuclei rna-seq reconstruction of adipose tissue reveals...
Biagi, Carlos Alberto Oliveira de; Cury, Sarah Santiloni [UNESP]; Alves, Cleidson Pádua; Rabhi, Nabil; Silva, Wilson Araujo; Farmer, Stephen R.Made available in DSpace on 2022-05-01T10:18:54Z (GMT). No. of bitstreams: 0 Previous issue date: 2021-11-01; Bundesministerium für Bildung und Forschung; American Historical Association; Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq); Deutsche Forschungsgemeinschaft; National Institutes of Health; Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP); Adipose tissue has been class...
Prediction of Non-canonical Routes for SARS-CoV-2 Infection in Human Placenta C...
Constantino, Flávia Bessi [UNESP]; Cury, Sarah Santiloni [UNESP]; Nogueira, Celia Regina [UNESP]; Carvalho, Robson Francisco [UNESP]Made available in DSpace on 2022-05-01T10:35:04Z (GMT). No. of bitstreams: 0 Previous issue date: 2021-11-08; The SARS-CoV-2 is the causative agent of the COVID-19 pandemic. The data available about COVID-19 during pregnancy have demonstrated placental infection; however, the mechanisms associated with intrauterine transmission of SARS-CoV-2 is still debated. Intriguingly, while canonical SARS-CoV-2 cell entry ...
Ascorbic acid supplementation improves skeletal muscle growth in pacu (Piaractu...
Zanella, Bruna Tereza Thomazini [UNESP]; Magiore, Isabele Cristina [UNESP]; Duran, Bruno Oliveira Silva; Pereira, Guilherme Gutierrez [UNESP]Made available in DSpace on 2021-06-25T10:55:21Z (GMT). No. of bitstreams: 0 Previous issue date: 2021-03-02; Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES); Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP); Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq); In fish, fasting leads to loss of muscle mass. This condition triggers oxidative stress, and therefore...