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Chemical composition and antifungal In vitro and in silico, antioxidant, and an...

Nascimento, José Eranildo Teles do; Rodrigues, Ana LivyaMoreira; Lisboa, Daniele Silva de; Liberato, Hortência Ribeiro; Falcão, Maria José Cajazeiras

Ouratea fieldingiana (Gardner) Engl is popularly used for wound healing. This study describes the main chemical compounds present in extracts of O. fieldingiana and evaluates their biological potential by investigating antifungal, antioxidant, and anticholinesterase activities.The actionmechanismofmain antifungal compound was investigated bymolecular docking using the enzyme sterol 14- demethylase, CYP51, requi...

Date: 2019   |   Origin: Oasisbr
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