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Estudio retrospectivo acerca de la evolución y el desarrollo de resistencias an...

Queirós, Catarina; Borges-Costa, João; Lito, L.; Filipe, Paulo; Cristino, José Melo

Background: Sexually Transmitted Infections remain a major public health concern worldwide. Although traditionally considered treatable, the emergence of Neisseria gonorrhoeae resistance to antimicrobials is currently a serious problem. The goal of this study was to evaluate the incidence and trends of antimicrobial resistance over the last 10 years in N. gonorrhoeae isolates from a Portuguese Centre. Methods: ...


A Case Report of Multibacillary Leprosy Presenting with Multiple Outbreaks of E...

Bouceiro-Mendes, R.; Ortins-Pina, A.; Marques, T.; Viveiros, M.; Machado, D.; Lito, L.; Ferreira, J.; Soares-de-Almeida, L.; Freitas, J. P.; Filipe, P.

Leprosy is a chronic granulomatous disease with a long incubation period caused by Mycobacterium leprae that mainly affects the skin, mucous membranes and the peripheral nervous system. It carries the risk of per-manent sequels with a significant impact on the patient’s quality of life. It has a considerable clinically diver-sity and possible atypical presentations. We present a case of a 31-year-old, skin phot...


Epidemiological survey of the first case of vancomycin-resistant Staphylococcus...

Friães, Ana; Resina, C.; Manuel, V.; Lito, L.; Ramirez, Mário; Cristino, José Melo

We report on the follow-up and epidemiological study triggered by the isolation of the first vancomycin-resistant Staphylococcus aureus (VRSA) detected in Europe. The patient and 53 close contacts were screened for S. aureus colonization and all isolates recovered were characterized by multiple molecular typing methods. The VRSA remained confined to the infected foot of the patient and was not detected in any o...


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