This work was supported in part through Battelle Memorial Institute?s prime contract with the US National Institute of Allergy and Infectious Diseases (NIAID) under Contract no. HHSN272200700016I (J. H. K.). This work was also funded in part by Grant 109520 by the UK Department of Health, Public Health England (R. H.). W. M. S. is supported by Funda??o de Amparo ? Pesquisa do Estado de S?o Paulo, Brazil (17/139...
OBJECTIVE: To assess the efficacy and safety of sitagliptin compared with voglibose added to combined metformin and insulin in patients with newly diagnosed type 2 diabetes (T2DM). METHODS: In this 12-week prospective, randomized, parallel trial, 70 newly diagnosed T2DM patients with glycosylated hemoglobin (HbA1c) X9% and/or fasting plasma glucose (FPG) X11.1 mmol/L were randomized (1:1) to receive sitagliptin...