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An oral nanomedicine elicits in situ vaccination effect against colorectal cancer
Zu, Menghang; Ma, Ya; Zhang, Jun; Sun, Jianfeng; Shahbazi, Mohammad-Ali; Pan, Guoqing; Reis, R. L.; Kundu, Subhas C; Liu, Jinyao; Xiao, BoOral administration is the most preferred approach for treating colon diseases, and in situ vaccination has emerged as a promising cancer therapeutic strategy. However, the lack of effective drug delivery platforms hampered the application of in situ vaccination strategy in oral treatment of colorectal cancer (CRC). Here, we construct an oral coreâ shell nanomedicine by preparing a silk fibroin-based dual s...
Date: 2024
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Origin: RepositóriUM - Universidade do Minho