3 documents found, page 1 of 1
Interferon gamma rebalances immunopathological signatures in chronic granulomat...
Bruno, M.; Kröger, C.; Ferreira, A. V.; Zhang, B.; Röring, R. J.; Liu, R.; van der Made, C. I.; van Rhijn, N.; Groh, L.; Klück, V.; Janssen, N. A. F.Chronic granulomatous disease (CGD) is a primary immunodeficiency characterized by recurrent life-threatening infections and hyperinflammatory complications. It is caused by mutations in the reduced nicotinamide adenine dinucleotide phosphate (NADPH) oxidase complex and the consequent loss of reactive oxygen species (ROS) production. Recombinant human interferon gamma (rIFN-γ) prophylaxis reduces the risk of se...
First Dark Matter Search Results from the LUX-ZEPLIN (LZ) Experiment
Aalbers, J.; Akerib, D. S.; Akerlof, C. W.; Al Musalhi, A. K.; Alder, F.; Alqahtani, A.; Alsum, S. K.; Amarasinghe, C. S.; Ames, A.; Anderson, T. J.9 pages, 8 figures. See https://doi.org/10.1103/PhysRevLett.131.041002 for a data release related to this paper; The LUX-ZEPLIN experiment is a dark matter detector centered on a dual-phase xenon time projection chamber operating at the Sanford Underground Research Facility in Lead, South Dakota, USA. This Letter reports results from LUX-ZEPLIN's first search for weakly interacting massive particles (WIMPs) wit...
The LUX-ZEPLIN (LZ) radioactivity and cleanliness control programs
Akerib, D. S.; Akerlof, C. W.; Akimov, D. Yu.; Alquahtani, A.; Alsum, S. K.; Anderson, T. J.; Angelides, N.; Araújo, H. M.; Arbuckle, A.LUX-ZEPLIN (LZ) is a second-generation direct dark matter experiment with spin-independent WIMPnucleon scattering sensitivity above 1.4 × 10−48 cm2 for a WIMP mass of 40 GeV/c2 and a 1000 days exposure. LZ achieves this sensitivity through a combination of a large 5.6 t fiducial volume, active inner and outer veto systems, and radio-pure construction using materials with inherently low radioactivity content. Th...