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Echinacea purpurea fractions represent promising plant-based anti-inflammatory ...

Vieira, Sara Filipa Fontoura; Gonçalves, Samuel M.; Gonçalves, Virgínia M. F.; Llaguno, Carmen P.; Macías, Felipe; Tiritan, Maria Elizabeth

Echinacea purpurea is traditionally used in the treatment of inflammatory diseases. Therefore, we investigated the anti-inflammatory capacity of E. purpurea dichloromethanolic (DE) and ethanolic extracts obtained from flowers and roots (R). To identify the class of compounds responsible for the strongest bioactivity, the extracts were fractionated into phenol/carboxylic acid (F1) and alkylamide fraction (F2)...


On the bioactivity of Echinacea purpurea extracts to modulate the production of...

Vieira, Sara F.; Gonçalves, Virgínia M. F.; Llaguno, Carmen P.; Macías, Felipe; Tiritan, Maria Elizabeth; Reis, R. L.

Inflammatory diseases are the focus of several clinical studies, due to limitations and serious side effects of available therapies. Plant-based drugs (e.g., salicylic acid, morphine) have become landmarks in the pharmaceutical field. Therefore, we investigated the immunomodulatory effects of flowers, leaves, and roots from <i>Echinacea purpurea</i>. Ethanolic (EE) and dichloromethanolic extracts (DE) were obta...


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