Meeting abstract in the European-Society-for-Medical-Oncology (ESMO) 21st World Congress on Gastrointestinal Cancer.
Terra é um planeta azul, em que 70% da superfície está ocupada por mar. Mais de 90% desse enorme volume está a profundidades superiores a 200 metros, onde a luz escasseia e a vida toma contornos diferentes dos que se observam nas zonas onde a energia solar penetra. O fundo do mar, na sua escuridão, é a última grande fronteira marinha a ser explorada. Denominado “mar profundo”, esse gigantesco ambiente, cujo pot...
Aminophilline is a substance widely used in respiratory diseases. Sometimes is used in a permanent and indiscriminate form, without the attention due to the potential toxic effect of this drug.Severe theophylline toxicity is associated with significant morbidity and mortality, due primarily to sustained or recurrent seizures, cardiovascular collapse and cardiac arrhythmias. In reference to a fatal clinical repo...
This paper describes an easy-to-fabricate and low-cost SU-8 microfluidic mixer suitable for enabling a mixing process based on diffusion. It is developed to be an integrated part of a lab-on-a-chip for measuring the concentration of four biomolecules in urine samples, by optical absorption. The design of the microfluidic system is based on computational fluid dynamics techniques. Mixing and reaction of the comp...
This paper describes a three-dimensional fluid dynamic model that is suitable for accurate simulation of on-chip liquid handling and mixing. The fluidic die (or mixer) is an integrated part of a biological microsystem for biological fluids analysis. It is designed for enabling a mixing process based on diffusion, which allows an easy-to-fabricate and low-cost mixer. The fabrication is based on planar technology...
It is well known that the thermal behaviour of moulds used for thermoplastics processing has an important effect on both the part quality and the process productivity. The present work reports a study on the evaluation of the relative effect of different geometric and operational parameters on the thermal behaviour of injection moulds. It uses a mathematical model developed to simulate the thermal transient exc...