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Engineered shape-tunable copper-coordinated nanoparticles for macrophage reprog...

Gao, Han; Cheng, Ruoyu; Cardoso, Inês; Lobita, Maria; Pacheco-Fernández, Idaira; Bártolo, Raquel; Rodrigues, L. R.; Hirvonen, Jouni; Santos, Hélder A.

The immune system safeguards as primary defense by recognizing nanomaterials and maintaining homeostasis, gaining a deeper understanding of these interactions may change the treating paradigm of immunotherapy. Here, we adopted copper as the principal component of nanoparticles (NPs), given its features of coordination with different benezenecarboxylate ligands to form metalorganic frameworks and complexes with ...


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