5 documents found, page 1 of 1
Impact of high‐risk human papilloma virus genotyping in cervical disease in the...
Rosário, Andreia; Sousa, Ana Saraiva; Marinho-Dias, Joana; Medeiros, Rui; Lobo, Cláudia; Leça, Luís; Coimbra, Nuno; Tavares, Fernando; Baldaque, InêsCervical cancer prevention is based on primary prevention with vaccines againstHuman Papillomavirus (HPV) and secondary prevention by screening with High‐Risk‐HPV (Hr‐HPV) detection. Since 2017, cervical cancer screening in women aged25−60 years has been performed in Portugal using Hr‐HPV detection, followed bycytology in Hr‐HPV‐positive cases. Herein we report the prevalence of Hr‐HPVgenotypes and cytological ...
Cytochemical characterization of ascitic fluid from a patient with ovarian canc...
Silva, Susana; Silva, Regina A.; Ferreira, Verónica; Lobo, Cláudia; Monteiro, Paula; Abreu, Miguel Henriques; Bartosch, Carla; Ricardo, SaraEpithelial ovarian cancer is the most lethal gynecological malignancy and peritoneal metastases are the leading cause of morbidity and mortality. Malignant cells shed from primary tumor and float in ascitic fluid, as single cells or multicellular spheroids, and later implant on the peritoneal lining.
High-Risk human papillomavirus genotype distribution in the Northern region of ...
Sousa, Hugo; Tavares, Ana; Campos, Carla; Marinho-Dias, Joana; Brito, Margarida; Medeiros, Rui; Baldaque, Inês; Lobo, Cláudia; Leça, LuísHigh-Risk Human papillomavirus (HR-HPV) full genotyping methods have been described as of great potential use in epidemiology and preventive strategies, including cervical cancer screening and HPV vaccination. We characterized the prevalence and distribution of HR-HPV genotypes in cervico-vaginal samples obtained from the Regional Cervical Cancer Screening Program from the Northern Region of Portugal. HR-HPV ge...
TERT promoter mutations are a major indicator of poor outcome in differentiated...
Melo, Miguel; Gaspar Da Rocha, Adriana; Vinagre, João; Batista, Rui; Peixoto, Joana; Tavares, Catarina; Celestino, Ricardo; Almeida, AnaContext: Telomerase promoter mutations (TERT) were recently described in follicular cell-derived thyroid carcinomas (FCDTC) and seem to be more prevalent in aggressive cancers. Objectives: We aimed to evaluate the frequency of TERT promoter mutations in thyroid lesions and to investigate the prognostic significance of such mutations in a large cohort of patients with differentiated thyroid carcinomas (DTCs). De...
Percentagem de indivíduos VIH e VHC positivos nos serviços do Hospital Amato Lu...
Torres, Sara; Lobo, Cláudia; Fernandes, Patrícia; Beato, Sílvia; Martins, MarianaAs infecções provocadas pelo VIH e VHC estão disseminadas por toda a população, sem atender ao extracto social, idade ou sexo. A partir de uma abordagem dos aspectos clínicos e epidemiológicos destes vírus e, sabendo que Portugal tem aproximadamente 12 milhões de habitantes, este artigo pretende identificar a percentagem de doentes com VIH e VHC positivos nos Serviços da Unidade Local de Saúde E.P.E. de Castelo...