6 documents found, page 1 of 1

Evolving hallmarks in urothelial bladder cancer: unveiling potential biomarkers

Urothelial bladder carcinoma (UBC), the most frequent type (90%) of bladder cancer and the second most common malignancy of the urogenital region, is a relatively well understood type of cancer, with numerous studies concerning pathogenetic pathways, natural history and bladder tumor biology being reported. Despite this, it continues to remain a challenge in the oncology field, mostly due to its relapsing and p...

Consequências da conjuntura económico-social na gestão sustentável da prevenção...

Um balanço feito recentemente da Estratégia 2020 para um crescimento inteligente, sustentável e inclusivo, revela que os desafios de 2010 não se resolveram e, em muitos aspetos, intensificaram-se. Mergulhada numa profunda crise económico-social, a Europa enfrenta hoje elevados desemprego, endividamento e pobreza, agravamento das desigualdades e, ainda que com assimetrias entre Estados-Membros, níveis pouco otim...

Electrochemical evaluation of the antioxidant capacity of hydroxylated benzylid...

Oxidative stress (OS) has been associated with a wide range of diseases such as atherosclerosis, cancer, and neurodegenerative disorders [1-3]. Oxidative stress occurs when intracellular oxidizing species, such as reactive oxygen species (ROS), increase abnormally and is often accompanied by a simultaneous loss of antioxidant capacity [4]. Therefore, the development and synthesis of new compounds (drugs) that a...

Caso clínico de “Widman Modificado”

Practical aspects of the use of target controlled infusion with remifentanil in...

Abstract Remifentanil has important side effects and it is not easy to know what remifentanil concentrations should be used during different endpoints of anaesthesia. We analyzed the remifentanil predicted effect-site concentrations (RemiCe) at different events during neurosurgical procedures and assessed if the concentrations used were clinically adequate. BIS and haemodynamic parameters were collected every 5...

The effect of a remifentanil bolus on the bispectral index of the EEG (BIS) in ...

Background and objective: Remifentanil boluses are used in different clinical situations and the effects on bispectral index monitoring are unclear. We analysed the effect of a remifentanil bolus on the bispectral index of the electroencephalogram (bispectral index) under total intravenous anaesthesia with propofol and remifentanil. Methods: ASA I–III patients were included in this study. All patients received ...