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The inflammation-related biomarker CXCR7 independently predicts patient outcome...

Santos, PB; Lobo, J; Félix, A; Silva, F; Manso, RT; Costa, J, et al.

INTRODUCTION: The influence of inflammation on prostate tumor carcinogenesis is currently much better known than with its role in prostate cancer (CaP) progression. We evaluated the prognostic value of epigenetic (HDAC1, HDAC4, H3Ac) and inflammation-related (CXCR4, CXCR7, CXCL12) biomarkers immunoexpression, in radical prostatectomy specimens, from 2 cohorts of CaP patients with long term follow-up. MATERIALS ...


Canine ovarian gonadoblastoma with dysgerminoma overgrowth: A case study and li...

Flores, AR; Lobo, J; Nunes, F; Rêma, A; Lopes, P; Carvalho, L; Bartosch, C; Amorim, I; Gärtner, F

Background: Gonadoblastoma (GB) is a rare mixed germ cell-sex cord-stromal tumour, first described in humans, commonly found in dysgenetic gonads of intersex patients that have a Y chromosome. However, this entity in not recognized in the WHO classification of tumours of genital system of domestic animals. Herein, we describe a case of ovarian gonadoblastoma with proliferation of dysgerminoma and sex cord-strom...


Epididymal metastasis from prostate adenocarcinoma: An unusual and challenging ...

Santos-Lopes, S; Lobo, J; Henrique, R; Oliveira, J

A few cases of prostate adenocarcinoma (PCa) metastases to the epididymis have been documented in literature. We report a case of a 69-year-old man with a left epididymal metastasis, 6 years after radical prostatectomy and adjuvant radiation therapy for PCa. Although he developed biochemical recurrence, only gallium-68 prostate-specific membrane antigen-positron emission tomography/computed tomography revealed ...


Síndrome de Sjögren

Brito, A; Figueirinhas, J; Ramos, M; Soares, AL; Neves, L; Lobo, J; Sousa e Faro, L

O presente trabalho consta de duas partes estando incluída na primeira a revisão teórica e conceitos actuais sobre o tema e na segunda, a casuística do serviço de Estomatologia do Hospital Pulido Valente. De Abril de 1989 a 1991 (2 anos) vem sendo realizado um estudo sobre o Síndrome de SJÖGREN (Primário e Secundário) de carácter multidisciplinar tendo tido a particular colaboração do Instituto Português de Reu...


Sjögren's syndrome.

Brito, A; Figueirinhas, J; Ramos, M; Soares, A L; Neves, L R; Lobo, J; Faro, L S

This paper consists the theorical review and the current concepts of the subject and the second includes the casuistry of the Stomatology Department of the Pulido Valente Hospital. From April 1989 to 1991 (2 years), a study was made on Sjögren Syndrome (Primary and Secondary) of multiple character with the particular co-operation of the Portuguese Institute of Rheumatology. With this paper we wish to point out ...

Date: 1994   |   Origin: Acta Médica Portuguesa

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