2 documents found, page 1 of 1
Characterization and qualification of diclofenac sodium as a secondary standard...
Stoef, Paulo Roberto; Guzzi, Silvane; Carletto, Marla Suzane; Lobo, Viviane da Silva; Rosa, Mauricio Ferreira daThis paper aimed to characterize and qualify a secondary standard of diclofenac sodium as a reference standard in the quality control of medicines. The identity of the candidate was confirmed through infrared spectroscopy and the content (99.63%) determined by high performance liquid chromatography (HPLC) by comparing with the compendial primary standard. The quality of the secondary standard was also supported...
Photodegradation of 4-((4-N,N-dimethylamine)-benzylidene)-2- phenyl-oxazolone i...
Rosa, Mauricio Ferreira da; Lobo, Viviane da Silva; Savariz, Franciele CristinaThirteen (13) oxazolone derivatives were synthesized and the photochemical behavior of one of them was analyzed for solvent polarity when submitted to irradiation in 350 nm. When acetonitrile is used as solvent, photodegradation is faster when compared with n-hexane. The electronic spectra in acetonitrile showed an isosbestic point in 419 nm, indicating that only two species co-exist in solution. The addition o...