5 documents found, page 1 of 1
A tailspike with exopolysaccharide depolymerase activity from a new Providencia...
Oliveira, Hugo Alexandre Mendes; Pinto, Graça; Mendes, B.; Dias, Oscar; Hendrix, Hanne; Akturk, Ergun; Noben, Jean-Paul; Gawor, Jan; Lobocka, MalgorzataProvidencia stuartii is emerging as a significant drug-resistant nosocomial pathogen, which encourages the search for alternative therapies. Here, we have isolated Providencia stuartii phage Stuart, a novel podovirus infecting multidrug-resistant hospital isolates of this bacterium. Phage Stuart is a proposed member of a new Autographivirinae subfamily genus, with a 41,218-bp genome, direct 345-bp repeats at vi...
Genome sequences of four potentially therapeutic bacteriophages infecting Shiga...
Dias, Carla Sofia Pereira; Almeida, Carina; Lobocka, Malgorzata; Oliveira, Hugo Alexandre MendesFour phages infecting Shiga toxin-producing Escherichia coli (STEC) strains of different serotypes were isolated from wastewater samples. Their virion DNAs range from 51 to 170 kbp, are circularly permuted or have defined terminal repeats, and can encode 82 to 279 proteins. Despite their high similarity to other phages, only about 30\% of their genes have a predicted function.
Taxonomy of prokaryotic viruses: 2017 update from the ICTV Bacterial and Archae...
Alfenas‐Zerbini, Poliane; Adriaenssens, Evelien M.; Wittmann, Johannes; Kuhn, Jens H.; Turner, Dann; Sullivan, Matthew B.; Dutilh, Bas E.; Jang, Ho BinThe prokaryotic virus community is represented at the Inter- national Committee on Taxonomy of Viruses (ICTV) by the Bacterial and Archaeal Viruses Subcommittee. Since our last report [5], the committee composition has changed, and a large number of taxonomic proposals (TaxoProps) were submitted to the ICTV Executive Committee (EC) for approval
Characterization and genomic analyses of two newly isolated Morganella phages d...
Oliveira, Hugo; Pinto, Graça; Oliveira, A.; Noben, Jean-Paul; Hendrix, Hanne; Lavigne, Rob; Lobocka, Malgorzata; Kropinski, Andrew M.; Azeredo, JoanaMorganella morganii is a common but frequent neglected environmental opportunistic pathogen which can cause deadly nosocomial infections. The increased number of multidrug-resistant M. morganii isolates motivates the search for alternative and effective antibacterials. We have isolated two novel obligatorily lytic M. morganii bacteriophages (vB_MmoM_MP1, vB_MmoP_MP2) and characterized them with respect to speci...
A lytic Providencia rettgeri virus of potential therapeutic value is a deep-bra...
Oliveira, Hugo Alexandre Mendes; Pinto, Graça; Hendrix, Hanne; Noben, Jean-Paul; Gawor, Jan; Kropinski, Andrew M.; Lobocka, Malgorzata; Lavigne, RobProvidencia rettgeri is emerging as a new opportunistic pathogen with high antibiotic resistance. The need to find alternative methods to control antibiotic-resistant bacteria and the recent advances in phage therapy motivate the search for new phages able to infect Providencia spp. This study describes the isolation and characterization of an obligatory lytic phage, vB_PreS_PR1 (PR1), with therapeutic potentia...