47 documents found, page 1 of 5

Nucleophile-induced fluorescence activation in Seleno-BODIPY

In this work, a seleno-BODIPY derivative (BDP-Se) was synthesized, and its reactivity towards a set of representative nucleophiles (including RNH2, PhO−, OH−, PhS−, among others) was investigated. Spectroscopic and kinetic studies were conducted, enabling a comparative evaluation of the reactivity of BDP-Se with the selected analytes. The structures of the resulting products were confirmed through mass spectrom...

Colorimetric and fluorometric Seleno-BODIPY sensor for selective palladium dete...

The fluorescent sensor based on Seleno-BODIPY (BDP-Se) was explored for the detection of palladium in samples of industrial and environmental interest. Colorimetric and fluorometric analyses were conducted, and the sensor demonstrated high selectivity for Pd2+ relative to 21 other cations, as well as high sensitivity (LOD = 0.31 μmol/L by fluorescence) in a turn-on fluorescence process. Quantification of Pd2+ i...

Fast ultrasonic-based extraction of peptides from teeth for forensics and archa...

This study presents a rapid, ultrasound-assisted solid-liquid extraction protocol for recovering peptides from the tooth surface, while preserving the macroscopically visible integrity of the dental morphology. The methodology described herein enables the concurrent use of a single peptide extraction for multiple analytical objectives, encompassing: (i) biological sex determination via detection of sex-dimorphi...

PVP formulations of bis-cyclometalated iridium(III) complexes bearing β-modifie...

Cancer stands as the second leading global cause of death, following heart disease. Considering the severe side effects revealed by some chemotherapeutics for tumor treatment and anticancer therapies, the scientific community is actively exploring more effective alternatives. Photodynamic Therapy (PDT) mediated by porphyrin-based photosensitizers (PS) has emerged as an attractive alternative to more conventiona...

Transformational Goal for Science Education

Limited access to hands-on laboratory equipment remains a significant barrier to effective science education. To address this challenge, we evaluated the analytical performance of the Doctor Vida® Education platform - an ultra-compact, low-cost, multifunctional analytical device designed under the ‘One Student–One Apparatus’ (1S1A) model. Using the Bradford method, we quantified total protein in urine and serum...

How to dissect viral infections and their interplay with the host-proteome by i...

The capabilities of bioanalytical mass spectrometry to (i) detect and differentiate viruses at the peptide level whilst maintaining high sample throughput and (ii) to provide diagnosis and prognosis for infected patients are presented as a tutorial in this work to aid analytical chemists and physicians to gain insights into the possibilities offered by current high-resolution mass spectrometry technology and bi...

How to dissect viral infections and their interplay with the host-proteome by i...

The capabilities of bioanalytical mass spectrometry to (i) detect and differentiate viruses at the peptide level whilst maintaining high sample throughput and (ii) to provide diagnosis and prognosis for infected patients are presented as a tutorial in this work to aid analytical chemists and physicians to gain insights into the possibilities offered by current high-resolution mass spectrometry technology and bi...

Lifetime and fluorescence quantum yield of two fluorescein-amino acid-based com...

N-confused porphyrin immobilized on solid supports: synthesis and metal ions se...

In this work, the N-confused porphyrin 5,10,15,20-tetraphenyl-2-aza-21-carbaporphyrin (NCTPP) was immobilized on neutral or cationic supports based on silica and on Merrifield resin. The new materials were characterized by appropriate techniques (UV-Vis spectroscopy, SEM, and zeta potential analysis). Piezoelectric quartz crystal gold electrodes were coated with the different hybrids and their ability to intera...

Metallomesogens with Luminescent Behaviour: Palladium Complexes Derived from Al...

A series of meso-tetraaryl-substituted free-base porphyrins containing different numbers of alkyl amide chains with different lengths, as well as the corresponding palladium(II) and platinum(II) complexes, were prepared in good yields and were fully characterised. The crystal structure of the palladium(II) complex containing eight alkyl chains with five carbon atoms was unequivocally elucidated by means of sing...