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Effect of indole alkaloids from roots of Rauvolfia ligustrina in the noradrener...

Magalhães, Herbert S.; Silva, Alison B.da; Nascimento, Nilberto Robson Falcão do; Sousa, Luis Gustavo F. de; Fonseca, Maria Júlia S. da

The new glucosyl sarpagan alkaloid designated as 21(R*)-(O-β-glucosyl)-hydroxy-sarpagan-17-oic acid, along with eleven known alkaloids were isolated from a soluble alkaloidal fraction from the ethanol extract of Rauvolfia ligustrina. Their structures were elucidated by interpretation of spectroscopic data (1D and 2D NMR), HRESIMS experiment, GIAO 13C NMR calculations, and comparison with literature data. All th...

Date: 2022   |   Origin: Oasisbr

Tropane alkaloids from the stem bark of Erythroxylum bezerrae

Brito, Luana San de O.; Pinto, Francisco das Chagas L.; Moraes Filho, Manoel Odorico de; Rocha, Danilo D.; Mendoza, Maria Fernanda M.

Six previously undescribed tropane alkaloids, designated as erythrobezerrines A-F, were isolated from the EtOH extract from the stem bark of Erythroxylum bezerrae Plowman. Their structures were elucidated based on the interpretation of the NMR and MS data and in some instances, confirmed by X-ray diffraction analysis. The cytotoxicity of the isolated compounds was evaluated against the cancer cell lines L929, P...

Date: 2022   |   Origin: Oasisbr

A new cheirolepidiaceous conifer Pseudofrenelopsis salesii sp. nov. from the Ea...

Batista, Maria Edenilce P.; Kunzmann, Lutz; Bezerra, Francisco Irineudo; Andrade, José Artur F. G. de; Sá, Artur A.; Loiola, Maria Iracema B.

Pseudofrenelopsis is a genus of the conifer family Cheirolepidiaceae, whose temporal distribution was restricted to the Early Cretaceous. Its set of features correspond to adaptive responses to rather unstable and stressful environ- mental conditions, such as aridity and/or groundwater salinity. In this paper, we describe Pseudofrenelopsis salesii sp. nov. from the Albian Romualdo Formation of the Araripe Basin...

Date: 2022   |   Origin: Oasisbr

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