7 documents found, page 1 of 1
Combination of gold nanoparticles with near-infrared light as an alternative ap...
Lopes, Joana; Rodrigues, Carla M; Godinho-Santos, Ana; Coelho, João M. P.; Cabaço, Luís C.; Barral, Duarte C.; Faísca, Pedro; Catarino, JoséCopyright © 2024. Published by Elsevier B.V.; Melanoma is the most aggressive type of skin cancer and recently approved drugs are often associated with resistance and significant adverse effects. Therefore, the design of more effective and safe options remains imperative. Photothermal therapy (PTT) using gold nanoparticles (AuNPs) presents a promising and innovative approach. In this work, the efficacy of combi...
Bioengineered exosomal-membrane-camouflaged abiotic nanocarriers
Lopes, Daniela; Lopes, Joana; Pereira-Silva, Miguel; Peixoto, Diana; Rabiee, Navid; Veiga, Francisco; Moradi, Omid; Guo, Zhan Hu; Wang, Xiang DongFunding This work was supported by grants from Fundação para a Ciência e Tecnologia (FCT) (SFRH/BD/148771/2019, 2021.05914.BD, PTDC/BTM-MAT/4738/2020), and also from the European Research Council—ERC Starting Grant (848325).; A bio-inspired strategy has recently been developed for camouflaging nanocarriers with biomembranes, such as natural cell membranes or subcellular structure-derived membranes. This strateg...
Exosome membrane-coated nanosystems
Shao, Minmin; Lopes, Daniela; Lopes, Joana; Yousefiasl, Satar; Macário-Soares, Ana; Peixoto, Diana; Ferreira-Faria, Inês; Veiga, Francisco; Conde, JoãoThe authors acknowledge the financial support from the grants 2021.05914.BD (given to D.P.) and PTDC/BTM-MAT/4738/2020 project (given to A.C.P.-S., J.C., and F.V.) from Fundacão para a Ciência e Tecnologia (FCT). J.C. acknowledges the European Research Council Starting Grant (ERC-StG-2019-848325).; Bio-mimicking principles have recently been proposed for the surface functionalization of nanoparticles (NPs). Suc...
Safety of Gold Nanoparticles
Lopes, Joana; Ferreira-Gonçalves, Tânia; Ascensão, Lia; Viana, Ana S.; Carvalho, Lina; Catarino, José; Faísca, Pedro; Oliva, AbelFunding Information: The authors acknowledge Fundação para a Ciência e a Tecnologia (FCT) for financial support through Projects UIDB/00645/2020, UIDB/04138/2020, UIDP/04138/2020, PTDC/BTM-MAT/31794/2017, and PTDC/QUI-QIN/0586/2020, as well as PhD fellowships SFRH/BD/148044/2019 and SFRH/BD/147306/2019. The authors are also thankful for the financial support to CESAM by FCT/MCTES (UIDP/50017/2020+UIDB/50017/202...
Single session subconvulsive electrical stimulation has rapid therapeutic effec...
Silva-dos-Santos, Amilcar; Youssef, Nagy A.; Bravo, Joana; Sales, Miguel; Velho, Maria Vaz; Simões, Fábio; Gaspar, Beatriz; Gracias, Maria JoãoFunding Information: Dr. Youssef discloses that in the last 3 years he has received support from the US National Institute of Health (NIH), Department of Veteran Affairs, Department of Defense, and the American Foundation of Suicide Prevention, as well as research support, but not salary support, from Merck & Co and the MECTA Corporation. He receives royalties from Elsevier Inc.Dr. Sackeim serves as a scientifi...
Macrophage Cell Membrane-Cloaked Nanoplatforms for Biomedical Applications
Lopes, Joana; Lopes, Daniela; Pereira-Silva, Miguel; Peixoto, Diana; Veiga, Francisco; Hamblin, Michael R.; Conde, João; Corbo, ClaudiaFunding: The authors acknowledge the financial support from the grants SFRH/ BD/148771/2019 (given to M.P.-S.) and 2021.05914.BD (given to D.P.), and PTDC/BTM-MAT/4738/2020 project (given to A.C.S. and J.C. (and also F.V., and M.P.-S.)) from Fundação para a Ciência e Tecnologia (FCT). Open access funding provided by Istituto Italiano di Tecnologia within the CRUI-CARE Agreement; Biomimetic approaches utilize na...
Preliminary assays towards melanoma cells using phototherapy with gold-based na...
Lopes, Joana; Coelho, João Miguel Pinto; Vieira, Pedro Manuel Cardoso; Viana, Ana Silveira; Gaspar, Maria Manuela; Reis, Catarina PintoUIDB/00645/2020 UID/DTP/04138/2019 PTDC/MED-QUI/31721/2017 SFRH/BD/148044/2019; Cancer like melanoma is a complex disease, for which standard therapies have significant adverse side effects that in most cases are ineffective and highly unspecific. Thus, a new paradigm has come with the need of achieving alternative (less invasive) and effective therapies. In this work, biocompatible gold nanoparticles (GNPs) co...